C75

SIGMA/C5490 - ≥98% (HPLC), powder

Synonym: 4-Methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid

CAS Number: 218137-86-1
Empirical Formula (Hill Notation): C₁₄H₂₂O₄
Molecular Weight: 254.32
MDL Number: MFCD03426157
Linear Formula: C₁₄H₂₂O₄
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-C5490-5MG	5 mg	$399.00 1/EA		Add To Favorites
45-C5490-25MG	25 mg	$1530.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to beige
form	powder
InChI	1S/C14H22O4/c1-3-4-5-6-7-8-9-11-12(13(15)16)10(2)14(17)18-11/h11-12H,2-9H2,1H3,(H,15,16)
InChI key	VCWLZDVWHQVAJU-UHFFFAOYSA-N
Quality Level	100
SMILES string	CCCCCCCCC1OC(=O)C(=C)C1C(O)=O
solubility	DMSO: 5 mg/mL, clear
storage temp.	2-8°C

Application:	C75 has been used: • as a fatty acid synthase (FASN) inhibitor to test its ability in the direct inhibition of FASN to attenuate mammosphere formation as compared to metformin • as a pharmacological inhibitor to inhibit fatty acid synthesis in glioma stem cells (GSCs) • as FAS inhibitor in the pre-treatment of Chang cells to inhibit lipogenesis and reverse the senescence induced by hydrogen peroxide
Biochem/physiol Actions:	C75 helps to increase the cancer‐killing capability of ionizing radiation.
Biochem/physiol Actions:	C75 is a novel, potent synthetic inhibitor of fatty acid synthase (FAS), which is used as a tool for studying fatty acid synthesis in metabolic disorders and cancer.
Packaging:	5, 25 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	41121801

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