Collagen from rabbit skin
SIGMA/C5608 - Bornstein and Traub Type I, powder
CAS Number: 9007-34-5
EC Number: 232-697-4
MDL Number: MFCD00130825
Product Type: Chemical
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| biological source | rabbit skin |
| description | acid soluble |
| form | powder |
| Quality Level | 200  |
| solubility | aqueous acid: ≤10 mg/mL |
| aqueous sodium acetate buffer: soluble (0.01-0.5M) | |
| storage temp. | 2-8°C |
| technique(s) | cell culture | stem cell: suitable |
| UniProt accession no. | Q28668  |
| Application: | Collagen-type 1 may be used in research of Idiopathic pulmonary fibrosis (IPF). Robust expression of collagen-type 1 is one distinctive feature of IPF. Additionally, collagen-type 1 has been used in studies on the effect of endoplasmic reticulum (ER) stress from IPF on myofibroblastic differentiation of lung fibroblasts. Collage-type 1 soluble in acidic solution produces three dimensional scaffolding useful in bioengineering and cell culture applications where biomaterials are needed to replace native collagen extracellular matrices. Collagen Type I has been used as a scaffold for the growth in vitro of stem cells in a wide variety of biomaterial engineering studies. |
| General description: | Collagen is classified into a number of structurally and genetically distinct types. We use the nomenclature proposed by Bornstein and Traub. Do not confuse Sigma type designations with recognized collagen classification types. |
| Preparation Note: | Prepared with modification of Gallop, P.M. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352202 |