CTAP

SIGMA/C6352 - ≥95%

CAS Number: 103429-32-9
Empirical Formula (Hill Notation): C₅₁H₆₉N₁₃O₁₁S₂
Molecular Weight: 1104.30
MDL Number: MFCD00671434
Linear Formula: C₅₁H₆₉N₁₃O₁₁S₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-C6352-1MG	1 mg	$263.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥95%
form	powder
InChI	1S/C51H69N13O11S2/c1-26(65)39(42(53)68)62-49(75)41-51(3,4)77-76-25-38(61-43(69)33(52)21-28-11-6-5-7-12-28)47(73)59-36(22-29-16-18-31(67)19-17-29)45(71)60-37(23-30-24-57-34-14-9-8-13-32(30)34)46(72)58-35(15-10-20-56-50(54)55)44(70)63-40(27(2)66)48(74)64-41/h5-9,11-14,16-19,24,26-27,33,35-41,57,65-67H,10,15,20-23,25,52H2,1-4H3,(H2,53,68)(H,58,72)(H,59,73)(H,60,71)(H,61,69)(H,62,75)(H,63,70)(H,64,74)(H4,54,55,56)/t26-,27-,33-,35+,36+,37-,38+,39+,40+,41-/m1/s1
InChI key	OFMQLVRLOGHAJI-FGHAYEPSSA-N
Quality Level	200
SMILES string	C[C@@H](O)[C@H](NC(=O)[C@H]1NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc4ccc(O)cc4)NC(=O)[C@H](CSSC1(C)C)NC(=O)[C@H](N)Cc5ccccc5)[C@@H](C)O)C(N)=O
storage temp.	−20°C
UniProt accession no.	Q62923

Amino Acid Sequence:	D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2
Application:	CTAP has been used as a μ-opioid receptor (MOR) antagonist: • to study the anti-hyperalgesic effect of dipeptidyl peptidase 4 (DPP4) inhibitor isoleucine-proline-isoleucine (IPI) and vildagliptin in carrageenan-induced inflammation • to study the role of MOR in glutamate and gamma-aminobutyric acid (GABA) efflux during predator stress in rats • to determine the endogenous opioid peptide involved in blocking pain induced by activated gastrin-releasing peptide (Grp⁺) neurons
Biochem/physiol Actions:	CTAP is a peptide antagonist produced from somatostatin analogs.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥95%
Storage Temp.	−20°C
UNSPSC	12352200

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