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CTB

SIGMA/C6499 - ≥98% (HPLC)

Synonym: CTPB; N-(4-Chloro-3-trifluoromethyl-phenyl)-2-ethoxy-benzamide

CAS Number: 451491-47-7
Empirical Formula (Hill Notation): C16H13ClF3NO2
Molecular Weight: 343.73
MDL Number: MFCD02356522
Linear Formula: C16H13ClF3NO2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-C6499-5MG 5 mg
 $92.70
1/EA		 Add To Favorites
45-C6499-25MG 25 mg
 $237.00
1/EA		 Add To Favorites
This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.

 

assay ≥98% (HPLC)
color white to off-white
form powder
InChI key YDXZSNHARVUYNM-UHFFFAOYSA-N
Quality Level 100 
SMILES string FC(F)(F)c1c(ccc(c1)NC(=O)c2c(cccc2)OCC)Cl
solubility DMSO: >10 mg/mL
storage temp. 2-8°C
Application: CTB has been used to study its apoptotic effects on P53 protein acetylation.
Biochem/physiol Actions: CBP (CREB binding protein)/p300) histone acetyltransferases (HATs) activator; p300 HAT activator.
Biochem/physiol Actions: CTPB was a first known small molecular activator of histone acetyltransferase p300. CTB is a simplified analog of CTPB with comparable or higher activity. The compound activates the histone acetyltransferase (HAT) activity of p300/EP300/E1A binding protein.
Biochem/physiol Actions: Small molecule activators of HAT such as CTB (N-(4-Chloro-3-trifluoromethyl-phenyl)-2-ethoxy-benzamide) is useful for altering chromatin acetylation directly. It might serve as a therapeutic agent for treating the complications of cognitive dysfunction including neuropsychiatric, neurodevelopmental and neurodegenerative diseases.
Features and Benefits: This compound is a featured product for Gene Regulation research. Click here  to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
General description: CTB (N-(4-Chloro-3-trifluoromethyl-phenyl)-2-ethoxy-benzamide) is derived from anacardic acid.
Packaging: 5, 25 mg in glass bottle
Hazard Codes Xi,N
Risk Statements 36-50/53
Safety Statements 26-60-61
RIDADR UN 3077 9 / PGIII
WGK Germany WGK 2
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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