Monoclonal Anti-c-Myc−Cy3™ antibody produced in mouse
SIGMA/C6594 - clone 9E10, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-c-Myc
Product Type: Chemical
Immunohistochemistry Formalin fixed, paraffin-embedded, Human colon carcinoma tissue sections were stained with 1:100 Monoclonal Anti-c-Myc-Cy3™ antibody produced in Mouse, Clone: 9E10 (Cat. No. C6594).
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 9E10, monoclonal |
| conjugate | CY3 conjugate |
| form | buffered aqueous solution |
| Quality Level | 200  |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | 2-8°C |
| target post-translational modification | unmodified |
| technique(s) | direct immunofluorescence: 1:50 using formalin-fixed, paraffin-embedded human colon carcinoma tissue |
| UniProt accession no. | P01106  |
| Application: | Monoclonal Anti-c-MycCy3™ antibody produced in mouse has been used in: • western blotting • immunocytochemistry • Immunofluorescence |
| Biochem/physiol Actions: | The encoded protein is involved in cell proliferation, growth and apoptosis. The c-myc gene has been implicated in the development of a number of neoplasms in a variety of avian and mammalian species. The human c-myc protooncogene is the cellular homolog of the avian v-myc gene found in several leukemogenic retroviruses. Increased expression of the cellular oncogene c-myc has been described in a variety of human tumors, occurring by several different mechanisms, including gene amplification and chromosomal translocation. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Monoclonal Anti-c-myc (mouse IgG1 isotype) is derived from the 9E10 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized BALB/c mouse. The c-Myc gene encodes a polypeptide with a predicted molecular weight of 49 kDa. |
| Immunogen: | synthetic peptide of the human p62c-Myc protein. |
| Legal Information: | Cy3 is a trademark of Cytiva |
| Physical form: | Solution in 0.01 M sodium phosphate buffered saline containing 1% bovine serum albumin and 15 mM sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352203 |