L-Cystine dihydrochloride
SIGMA/C6727 - from non-animal source, BioReagent, suitable for cell culture, ≥98.0% dry basis
Synonym: Cystine dihydrochloride
CAS Number: 30925-07-6
Empirical Formula (Hill Notation): C6H12N2O4S2 · 2HCl
Molecular Weight: 313.22
EC Number: 250-391-9
MDL Number: MFCD00070399
Linear Formula: C6H12N2O4S2 · 2HCl
Product Type: Chemical
| assay | ≥98.0% dry basis |
| biological source | non-animal source |
| cation traces | As: ≤2 ppm |
| Fe: ≤30 ppm | |
| heavy metals: ≤10 ppm | |
| NH4+: ≤0.03% | |
| color | white to off-white |
| form | powder or crystals |
| functional group | carboxylic acid |
| thiol | |
| impurities | endotoxin, tested |
| InChI | 1S/C6H12N2O4S2.2ClH/c7-3( |
| InChI key | HHGZUQPEIHGQST-RGVONZFCSA |
| mp | ≥211.36 °C |
| optical activity | [α]20/D -174 to -164 °, c = 2 in 1 M HCl |
| product line | BioReagent |
| Quality Level | 300 ![]() |
| SMILES string | Cl.Cl.N[C@@H](CSSC[C@H](N |
| solubility | 2 M HCl: 50 mg/mL |
| storage temp. | room temp |
| technique(s) | cell culture | mammalian: suitable |
| Application: | L-cystine dihydrochloride has been used: • as a supplement to study homopropargylglycine update in metabolomics • as a supplement in protein synthesis for cell biology and stem cell research • to study the effect of lipid peroxidation and ferroptosis by regulation of cysteine and GSH levels in biochemical research |
| Biochem/physiol Actions: | Cystine is the dimeric form of cysteine. Cysteine is the source of disulfide linkages in proteins and has a role in sulfur transport. It undergoes rapid oxidation to form cystine at physiological pH. L-Cystine is crucial for oxygen production and low density lipoprotein modification by arterial smooth muscle cells. It also has a role in the synthesis of glutathione. |
| Disclaimer: | hygroscopic |
| Features and Benefits: | • High-quality compound suitable for multiple research applications • Suitable for mammalian cell culture • Prepared from non-animal source • Tested for Endotoxins |
| General description: | L-Cystine dihydrochloride is a vital component of biological systems, and its role in protein structure, redox chemistry, and cellular processes makes it a valuable tool in Biology and Chemistry research across a wide range of applications, from understanding fundamental biochemical mechanisms to drug development and nutritional research. L-Cystine is essential for studying protein structure and function. It can be used to create disulfide bonds in proteins, aiding in the formation of protein complexes and the stabilization of protein structures. This is particularly important in biotechnology and pharmaceutical research. |
| Other Notes: | For additional information on our range of Biochemicals , please complete this form . |
| Packaging: | 1 kg in poly bottle |
| Packaging: | 25, 100 g in poly bottle |
| Symbol | GHS05 |
| Signal word | Danger |
| Hazard statements | H314 |
| Precautionary statements | P260 - P280 - P303 + P361 + P353 - P305 + P351 + P338 + P310 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98.0% dry basis |
| mp | ≥211.36 °C |
| Storage Temp. | room temp |
| UNSPSC | 12352209 |


