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Chondroitin sulfate sodium salt from bovine cartilage

SIGMA/C6737 - 98-102% (CPC, titration)

CAS Number: 9082-07-9
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-C6737-5G 5 g
$375.00
1/EA
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assay 98-102% (CPC, titration)
biological source bovine cartilage
cation traces Na: 7.4-8.8% (anhydrous)
color white to off-white
form powder
grade standard (for CPC (cetylpyridinium chloride) titration)
impurities <10.0% water (Karl Fischer)
InChI 1S/C14H23NO15S.Na/c1-3(17)15-5-10(9(30-31(24,25)26)4(2-16)27-13(5)23)28-14-8(20)6(18)7(19)11(29-14)12(21)22;/h4-11,13-14,16,18-20,23H,2H2,1H3,(H,15,17)(H,21,22)(H,24,25,26);/q;+1/p-1/t4-,5-,6-,7-,8+,9+,10-,11+,13-,14+;/m1./s1
InChI key SHQAYVXGAAXVHV-GNAIRZFJSA-M
optical activity [α]20/D -30 to -20 °, c = 5% (w/v) in water
Quality Level 200 
SMILES string [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@H]2O[C@@H]([C@H](O)[C@@H](O)[C@@H]2O)C(O)=O
solubility H2O: soluble 50 mg/mL, clear to hazy, colorless to faintly yellow
storage temp. 2-8°C
Application: Chondroitin sulfate, a glucosaminoglycan (GAG) polysaccharide chain of alternating units of N-acetylgalactosamine (GalNAc) and glucuronic acid (GlcA), is used in a wide variety of areas of research including bioengineering. Chondroitin sulfate may be used as a biomaterial copolymer or surface derivatization reagent in the development of drug delivery vehicles, tissue engineering devices and bioscaffolds. Chondroitin sulfate may be used for the development of biocompatible structures such as hydrogels, sponges, biofilms, microspheres and micelles.
Biochem/physiol Actions: As a large, negatively charged, hydrophilic molecule that is too inflexible to fold into a compact globular structure, chondroitin sulfate molecules form porous hydrated gels, providing mechanical support to tissue and allowing rapid diffusion of water-soluble molecules and migration of cells.
Disclaimer: Store this product at 2-8°C.
General description: Chondroitin, a glucosaminoglycan (GAG), is a polysaccharide chain of alternating units of N-acetylgalactosamine (GalNAc) and glucuronic acid (GlcA) that can be sulfated on the either or both GalNAc and GlcA units. Chondroitin and its sulfates are frequently attached to proteins to form proteoglycans.
Other Notes: Chondroitin is an acidic mucopolysaccharide found in cartilage, skin, cornea, and umbilical cord. It is composed of alternating N-acetylgalactosamine, D-glucuronic acid, and sulfate residues in equimolar quantities that can be sulfated on either of its subunits. Sulfation can occur at the 6 and/or 4-position of the galactosamine moiety, with potential for any individual disaccharide unit to be 6-sulfated, 4-sulfated, 4,6-disulfated, or unsulfated.
Other Notes: To gain a comprehensive understanding of our extensive range of Polysaccharides  for your research, we encourage you to visit our Carbohydrates  Category page.
Packaging: 5 g in poly bottle
Preparation Note: This product is soluble in water at 100 mg/mL.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity 98-102% (CPC, titration)
Storage Temp. 2-8°C
UNSPSC 12352201

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