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Congo Red

SIGMA/C6767 - Dye content ≥35 %

Synonym: Congo Red 4B; Cosmos Red; Cotton Red B; Cotton Red C; Direct Red 28; Direct Red R; Direct Red Y

CAS Number: 573-58-0
Empirical Formula (Hill Notation): C32H22N6Na2O6S2
Molecular Weight: 696.66
EC Number: 209-358-4
MDL Number: MFCD00004028
Linear Formula: C32H22N6Na2O6S2
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-C6767-25G 25 g
$27.20
1/EA
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45-C6767-100G 100 g
$76.50
1/EA
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application(s) diagnostic assay manufacturing
hematology
histology
color red-brown
composition Dye content, ≥35%
form powder
InChI 1S/C32H24N6O6S2.2Na/c33-31-25-7-3-1-5-23(25)29(45(39,40)41)17-27(31)37-35-21-13-9-19(10-14-21)20-11-15-22(16-12-20)36-38-28-18-30(46(42,43)44)24-6-2-4-8-26(24)32(28)34;;/h1-18H,33-34H2,(H,39,40,41)(H,42,43,44);;/q;2*+1/p-2/b37-35+,38-36+;;
InChI key IQFVPQOLBLOTPF-HKXUKFGYSA-L
mp >360 °C (lit.)
pH 6.7 (10 g/L)
Quality Level 200 
SMILES string [Na+].[Na+].Nc1c(cc(c2ccccc12)S([O-])(=O)=O)N=Nc3ccc(cc3)-c4ccc(cc4)N=Nc5cc(c6ccccc6c5N)S([O-])(=O)=O
solubility H2O: 1 mg/mL
storage temp. room temp
technique(s) titration: suitable
Application: • Congo red has been used as a histochemical stain for the quantification of amyloid deposits in brain tissues.
• It has been used as a cell wall inhibiting agent in fungus Cryptococcus neoformans.
• It has also been used to study microstructural details in the cell walls of raw potato and fried potato using confocal microscopy.
Biochem/physiol Actions: Congo red is a benzidine-based anionic diazo dye. It is a histological dye which binds to many amyloid proteins and is used for the quantification of amyloid β-peptide aggregation. Congo red also interacts with β-D-glucans, polysaccharides containing continuous β-(1→4)-linked D-glucopyranosyl units and some hemicellulosic galactoglucomannans.
Packaging: 25, 100 g in poly bottle
mp >360 °C (lit.)
Storage Temp. room temp
Colour Index Number 22120
UNSPSC 12171500

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