Congo Red
SIGMA/C6767 - Dye content ≥35 %
Synonym: Congo Red 4B; Cosmos Red; Cotton Red B; Cotton Red C; Direct Red 28; Direct Red R; Direct Red Y
CAS Number: 573-58-0
Empirical Formula (Hill Notation): C32H22N6Na2O6S2
Molecular Weight: 696.66
EC Number: 209-358-4
MDL Number: MFCD00004028
Linear Formula: C32H22N6Na2O6S2
Product Type: Chemical
| application(s) | diagnostic assay manufacturing hematology histology |
| color | red-brown |
| composition | Dye content, ≥35% |
| form | powder |
| InChI | 1S/C32H24N6O6S2.2Na/c33-3 |
| InChI key | IQFVPQOLBLOTPF-HKXUKFGYSA |
| mp | >360 °C (lit.) |
| pH | 6.7 (10 g/L) |
| Quality Level | 200 ![]() |
| SMILES string | [Na+].[Na+].Nc1c(cc(c2ccc |
| solubility | H2O: 1 mg/mL |
| storage temp. | room temp |
| technique(s) | titration: suitable |
| Application: | • Congo red has been used as a histochemical stain for the quantification of amyloid deposits in brain tissues. • It has been used as a cell wall inhibiting agent in fungus Cryptococcus neoformans. • It has also been used to study microstructural details in the cell walls of raw potato and fried potato using confocal microscopy. |
| Biochem/physiol Actions: | Congo red is a benzidine-based anionic diazo dye. It is a histological dye which binds to many amyloid proteins and is used for the quantification of amyloid β-peptide aggregation. Congo red also interacts with β-D-glucans, polysaccharides containing continuous β-(1→4)-linked D-glucopyranosyl units and some hemicellulosic galactoglucomannans. |
| Packaging: | 25, 100 g in poly bottle |
| Symbol | GHS08 |
| Signal word | Danger |
| Hazard statements | H350 - H361d |
| Precautionary statements | P201 - P202 - P280 - P308 + P313 - P405 - P501 |
| Hazard Codes | T |
| Risk Statements | 45-63-36 |
| Safety Statements | 53-45 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| mp | >360 °C (lit.) |
| Storage Temp. | room temp |
| Colour Index Number | 22120 |
| UNSPSC | 12171500 |


