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Cefaclor

SIGMA/C6895

Synonym: 7-(D-2-Amino-2-phenylacetamido)-3-chloro-3-cephem-4-carboxylic acid

CAS Number: 53994-73-3
Empirical Formula (Hill Notation): C15H14ClN3O4S
Molecular Weight: 367.81
EC Number: 258-909-5
MDL Number: MFCD00151471
Linear Formula: C15H14ClN3O4S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-C6895-1G 1 g
 $292.00
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This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: C6895-1G

 

antibiotic activity spectrum Gram-negative bacteria
  Gram-positive bacteria
form powder or crystals
InChI 1S/C15H14ClN3O4S/c16-8-6-24-14-10(13(21)19(14)11(8)15(22)23)18-12(20)9(17)7-4-2-1-3-5-7/h1-5,9-10,14H,6,17H2,(H,18,20)(H,22,23)/t9-,10-,14-/m1/s1
InChI key QYIYFLOTGYLRGG-GPCCPHFNSA-N
mode of action cell wall synthesis | interferes
Quality Level 200 
SMILES string N[C@@H](C(=O)N[C@H]1[C@H]2SCC(Cl)=C(N2C1=O)C(O)=O)c3ccccc3
solubility soluble (slightly soluble in water, practically insoluble in methanol, ethanol)
Application: Cefaclor has been used in the heterologous expression of AaOr7 and AaOr8 in Xenopus laevis oocytes. It has also been used in cultures of isolated trigeminal ganglion (TG) and dorsal root ganglion (DRG) neurons.
Application: Cefaclor is used to study urinary tract, intra-abdominal, and Haemophilus influenzae infections . It is used to study the mechanism of human renal organic anion and peptide transporters such as hOAT1, hPEPT1, and hPEPT2 and to study the effects of inhibition of penicillin-binding proteins on bacterial cell wall mucopeptide synthesis .
Biochem/physiol Actions: Cefaclor is a second generation cephalosporin with broad spectrum activity against Gram-negative and Gram-positive bacteria. It binds to penicillin-binding proteins and thereby inhibits the cell wall synthesis causing cell death.
General description: Chemical structure: ß-lactam
Other Notes: Keep container tightly closed in a dry and well-ventilated place. Slightly soluble in water, practically insoluble in methanol, chloroform and benzene.
Hazard Codes Xn
Risk Statements 42/43
Safety Statements 22-36/37-45
RIDADR NONH for all modes of transport
WGK Germany WGK 2
Flash Point(F) Not applicable
Flash Point(C) Not applicable
UNSPSC 51283701

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