β-Casein from bovine milk

SIGMA/C6905 - BioUltra, ≥98% (PAGE)

CAS Number: 9000-71-9
EC Number: 232-555-1
MDL Number: MFCD00130619
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-C6905-250MG	250 mg	$87.80 1/EAAdd To Favorites		Add To Favorites
45-C6905-1G	1 g	$266.00 1/EAAdd To Favorites		Add To Favorites

PAGE (4-20%) of β-Casein from bovine milk (Cat. No. C6905) under native conditions and stained with Coomassie Blue.

assay	≥98% (PAGE)
biological source	bovine milk
form	essentially salt-free, lyophilized powder
InChI	1S/C81H125N22O39P/c1-36(2)31-50(76(132)94-43(15-24-57(87)108)71(127)101-52(34-64(120)121)78(134)98-49(81(137)138)11-7-8-30-82)99-72(128)47(19-28-61(114)115)95-77(133)51(33-63(118)119)100-73(129)48(20-29-62(116)117)97-80(136)65(37(3)104)103-75(131)44(16-25-58(88)109)92-68(124)42(14-23-56(86)107)90-67(123)41(13-22-55(85)106)91-69(125)45(17-26-59(110)111)93-70(126)46(18-27-60(112)113)96-79(135)53(35-142-143(139,140)141)102-74(130)40(12-21-54(84)105)89-66(122)39(83)32-38-9-5-4-6-10-38/h4-6,9-10,36-37,39-53,65,104H,7-8,11-35,82-83H2,1-3H3,(H2,84,105)(H2,85,106)(H2,86,107)(H2,87,108)(H2,88,109)(H,89,122)(H,90,123)(H,91,125)(H,92,124)(H,93,126)(H,94,132)(H,95,133)(H,96,135)(H,97,136)(H,98,134)(H,99,128)(H,100,129)(H,101,127)(H,102,130)(H,103,131)(H,110,111)(H,112,113)(H,114,115)(H,116,117)(H,118,119)(H,120,121)(H,137,138)(H2,139,140,141)
InChI key	BECPQYXYKAMYBN-UHFFFAOYSA-N
product line	BioUltra
Quality Level	300
storage temp.	−20°C
technique(s)	activity assay: suitable
UniProt accession no.	P02666
	P02668

Application:	It has been studied as a generator of peptides responsible for biological activities such as opiate, immunostimulating, antibacterial, and peptidase inhibitors.
Application:	β-Casein from bovine milk has been used as a protein substrate in proteolytic assays. It has also been used to embed polyacrylamide gels in β-casein zymography.
Biochem/physiol Actions:	A polymorphic fraction of the major milk protein, casein. The A1 and B (but not A2) isoforms yield the bioactive peptide, ß-casomorphin upon gastrointestinal proteolytic digestion, which can have widely varied effects on human health. There is some effort to select dairy cattle for the A2 isoform to avoid this possibility.
General description:	β-Casein from bovine milk is an immunoglobulin E (IgE)-binding epitope belonging to the secretory calcium-binding phosphoprotein family. It consists of 209 amino acids and five phosphate groups. β-Casein has a globular hydrophobic domain at the C-terminal, a highly solvated and charged domain at the N-terminal and proline residues.
Packaging:	1 g in poly bottle
Packaging:	250 mg in poly bottle