Cefotaxime sodium salt

SIGMA/C7039 - suitable for plant cell culture, BioReagent, powder or crystals

Synonym: Cefotaxim sodium salt

CAS Number: 64485-93-4
Empirical Formula (Hill Notation): C₁₆H₁₆N₅NaO₇S₂
Molecular Weight: 477.45
EC Number: 264-915-9
MDL Number: MFCD00079073
Linear Formula: C₁₆H₁₆N₅NaO₇S₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-C7039-100MG	100 mg	$66.40 1/EA	Add To Favorites
45-C7039-500MG	500 mg	$200.00 1/EA	Add To Favorites
45-C7039-1G	1 g	$326.00 1/EA	Add To Favorites
45-C7039-5G	5 g	$1280.00 1/EA	Add To Favorites
45-C7039-10G	10 g	$1960.00 1/EA	Add To Favorites

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Properties
Descriptions
Safety Info.
Basic Data

antibiotic activity spectrum	Gram-negative bacteria
	Gram-positive bacteria
application(s)	agriculture
color	off-white to pale yellow
form	powder or crystals
InChI	1S/C16H17N5O7S2.Na/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8;/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26);/q;+1/p-1/b20-9-;/t10-,14-;/m1./s1
InChI key	AZZMGZXNTDTSME-JUZDKLSSSA-M
mode of action	cell wall synthesis \| interferes
product line	BioReagent
Quality Level	200
SMILES string	[Na+].[H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)c3csc(N)n3)C([O-])=O
solubility	H₂O: 10% ( )
storage temp.	2-8°C
technique(s)	cell culture \| plant: suitable

Application:	Cefotaxime sodium salt has been used as an test antibiotic in antibiotic susceptibility testing (AST) methods. It has also been used as an antibiotic to remove bacteria from O. tauri cultures.
Biochem/physiol Actions:	Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.
Biochem/physiol Actions:	Cefotaxime, a cephalosporin antibiotic, is active against both gram-negative and gram-positive bacteria. In addition, cefotaxime blocks the division of cyanobacteria. It also has an ability to inhibit the cell division of lower plant organelles/plastids such as the photosynthetic organelles of glaucophytes and chloroplasts of bryophytes.
Biochem/physiol Actions:	Mode of Action: Inhibits bacterial cell wall synthesis.
General description:	Chemical structure: ß-lactam
Other Notes:	Broad spectrum third generation cephalosporin antibiotic.
Other Notes:	Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place. Keep in a dry place.

Symbol	GHS08
Signal word	Danger
Hazard statements	H317 - H334
Precautionary statements	P261 - P280 - P342 + P311
Hazard Codes	Xn
Risk Statements	42/43
Safety Statements	22-36/37
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Storage Temp.	2-8°C
UNSPSC	10171502

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