Cefotaxime sodium salt
SIGMA/C7039 - suitable for plant cell culture, BioReagent, powder or crystals
Synonym: Cefotaxim sodium salt
CAS Number: 64485-93-4
Empirical Formula (Hill Notation): C16H16N5NaO7S2
Molecular Weight: 477.45
EC Number: 264-915-9
MDL Number: MFCD00079073
Linear Formula: C16H16N5NaO7S2
Product Type: Chemical
| antibiotic activity spectrum | Gram-negative bacteria |
| Gram-positive bacteria | |
| application(s) | agriculture |
| color | off-white to pale yellow |
| form | powder or crystals |
| InChI | 1S/C16H17N5O7S2.Na/c1-6(2 |
| InChI key | AZZMGZXNTDTSME-JUZDKLSSSA |
| mode of action | cell wall synthesis | interferes |
| product line | BioReagent |
| Quality Level | 200 ![]() |
| SMILES string | [Na+].[H][C@]12SCC(COC(C) |
| solubility | H2O: 10% ( ) |
| storage temp. | 2-8°C |
| technique(s) | cell culture | plant: suitable |
| Application: | Cefotaxime sodium salt has been used as an test antibiotic in antibiotic susceptibility testing (AST) methods. It has also been used as an antibiotic to remove bacteria from O. tauri cultures. |
| Biochem/physiol Actions: | Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes. |
| Biochem/physiol Actions: | Cefotaxime, a cephalosporin antibiotic, is active against both gram-negative and gram-positive bacteria. In addition, cefotaxime blocks the division of cyanobacteria. It also has an ability to inhibit the cell division of lower plant organelles/plastids such as the photosynthetic organelles of glaucophytes and chloroplasts of bryophytes. |
| Biochem/physiol Actions: | Mode of Action: Inhibits bacterial cell wall synthesis. |
| General description: | Chemical structure: ß-lactam |
| Other Notes: | Broad spectrum third generation cephalosporin antibiotic. |
| Other Notes: | Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place. Keep in a dry place. |
| Symbol | GHS08 |
| Signal word | Danger |
| Hazard statements | H317 - H334 |
| Precautionary statements | P261 - P280 - P342 + P311 |
| Hazard Codes | Xn |
| Risk Statements | 42/43 |
| Safety Statements | 22-36/37 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 10171502 |


