Casein from bovine milk

SIGMA/C7078 - technical grade

CAS Number: 9000-71-9
EC Number: 232-555-1
MDL Number: MFCD00081481
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-C7078-500G	500 g	$64.40 1/EA	Add To Favorites
45-C7078-1KG	1 kg	$110.00 1/EA	Add To Favorites
45-C7078-10KG	10 kg	$698.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: C7078-500G

Properties
Descriptions
Safety Info.
Basic Data

biological source	bovine milk
form	powder
grade	technical grade
InChI	1S/C81H125N22O39P/c1-36(2)31-50(76(132)94-43(15-24-57(87)108)71(127)101-52(34-64(120)121)78(134)98-49(81(137)138)11-7-8-30-82)99-72(128)47(19-28-61(114)115)95-77(133)51(33-63(118)119)100-73(129)48(20-29-62(116)117)97-80(136)65(37(3)104)103-75(131)44(16-25-58(88)109)92-68(124)42(14-23-56(86)107)90-67(123)41(13-22-55(85)106)91-69(125)45(17-26-59(110)111)93-70(126)46(18-27-60(112)113)96-79(135)53(35-142-143(139,140)141)102-74(130)40(12-21-54(84)105)89-66(122)39(83)32-38-9-5-4-6-10-38/h4-6,9-10,36-37,39-53,65,104H,7-8,11-35,82-83H2,1-3H3,(H2,84,105)(H2,85,106)(H2,86,107)(H2,87,108)(H2,88,109)(H,89,122)(H,90,123)(H,91,125)(H,92,124)(H,93,126)(H,94,132)(H,95,133)(H,96,135)(H,97,136)(H,98,134)(H,99,128)(H,100,129)(H,101,127)(H,102,130)(H,103,131)(H,110,111)(H,112,113)(H,114,115)(H,116,117)(H,118,119)(H,120,121)(H,137,138)(H2,139,140,141)
InChI key	BECPQYXYKAMYBN-UHFFFAOYSA-N
mp	280 °C (dec.) (lit.)
Quality Level	300
SMILES string	[P](=O)(OCC(NC(=O)C(NC(=O)C(N)Cc1ccccc1)CCC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(C(O)C)C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(CC(=O)O)C(=O)NC(C
technique(s)	activity assay: suitable
	electrophoresis: suitable
	immunocytochemistry: suitable
UniProt accession no.	P02662
	P02663
	P02666

Application:	Casein from bovine milk has been used as: • a blocking agent in immunochemistry • a substrate to determine the casinolytic activity in disintegrin and Cerastes cerastes venom • as a fining agent to test its effect on white wine protein stabilization
Application:	Casein from bovine milk is a phosphoprotein. There are four main types of Casein which make up approximately 80% of the total protein in bovine milk: α-s1 Casein, α-s2 Casein, β-Casein, and κ-Casein. Casein is proposed to be the main protective constituent in milk
Biochem/physiol Actions:	Casein finds application in nutraceuticals and various formulations such as hydrogels, films, nano micelles, and nanoparticles due to its properties such as emulsification, foaming, gelation, water-holding capacity, and interaction with bioactive molecules through functional groups. This protein is easily available, and it protects drugs from enzymatic degradation and nontoxicity so, casein is potentially used in oral delivery systems.
Biochem/physiol Actions:	Partial gastrointestinal digestion of casein is a rich source of bioactive peptides, such as β-casomorphin. However, bovine casein is not homogeneous; variants A1 and B do lead to production of β-casomorphin 7 production, while A2 does not.
General description:	Casein from bovine milk is a phosphoprotein. There are four main types of casein which make up approximately 80% of the total protein in bovine milk: α-_s1 Casein, α-_s2 Casein, β-Casein, and κ-Casein. Casein is proposed to be the main protective constituent in milk and is generally recognized as safe (GRAS) due to its naturally biocompatible and biodegradable properties.
Other Notes:	This product is technical grade casein. When compared to partially purified casein products, the technical grade has more protein impurities present and higher fat content.
Packaging:	1 kg in poly bottle
Packaging:	10 kg in poly drum
Packaging:	500 g in poly bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 1

mp	280 °C (dec.) (lit.)
UNSPSC	12352202

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