L-Cystine
SIGMA/C7602 - from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-101.0%
Synonym: (R,R)-3,3′-Dithiobis(2-aminopropionicacid)
CAS Number: 56-89-3
Empirical Formula (Hill Notation): C6H12N2O4S2
Molecular Weight: 240.30
EC Number: 200-296-3
MDL Number: MFCD00064228
Linear Formula: [-SCH2CH(NH2)CO2H]2
Product Type: Chemical
agency | meets EP testing specifications |
application(s) | peptide synthesis |
assay | 98.5-101.0% |
biological source | non-animal source |
color | white to off-white |
form | powder |
impurities | endotoxin, tested |
InChI | 1S/C6H12N2O4S2/c7-3(5(9)1 |
InChI key | LEVWYRKDKASIDU-IMJSIDKUSA |
mp | >240 °C (dec.) (lit.) |
product line | BioXtra |
SMILES string | N[C@@H](CSSC[C@H](N)C(O)= |
solubility | 1 M HCl: 100 mg/mL |
technique(s) | cell culture | mammalian: suitable |
Application: | L-Cystine has been used as a supplement in astroglial-conditioned media to culture cerebral astroglia. It has been used in several techniques, such as HPLC-FD, UHPLC-UV, UHPLC-MS, and triple quadrupole tandem mass spectrometry (UHPLC-MS/MS), to differentiate BMAA (β-N-methylamino-L-alanine), the cyanobacterial neurotoxin, from other diamino acids. L-Cystine has been used as a supplement in oocyte culture media to improve oocyte maturation and parthenogenesis of embryonic development. |
Biochem/physiol Actions: | Cystinuria is characterized with renal transport and excretion of L-Cystine. Cysteine is one of the functional amino acids that are associated with growth, reproduction, maintenance and immunity. Cysteine is a source of disulfide linkage in protein and is associated with sulfur transport. At physiological pH, cysteine undergoes rapid oxidation to form cystine. Reduced availability of cysteine or cystine, influences leukocyte metabolism. L-Cystine is necessary for oxygen production and LDL (low density lipoprotein) modification by arterial smooth muscle cells. |
Packaging: | 1 kg in poly bottle |
Packaging: | 10 mg in glass bottle |
Packaging: | 25, 100 g in poly bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 1 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | 98.5-101.0% |
mp | >240 °C (dec.) (lit.) |
UNSPSC | 12352209 |