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Concanavalin A from Canavalia ensiformis (Jack bean)

SIGMA/C7642 - FITC conjugate, Type IV, lyophilized powder

Synonym: ConA

Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-C7642-2MG 2 mg
 $87.20
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45-C7642-10MG 10 mg
 $178.00
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This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.

 

biological source Canavalia ensiformis
composition Protein, 5-15% biuret
conjugate FITC conjugate
extent of labeling 3-6 mol FITC per mol protein
form lyophilized powder
impurities Carbohydrate, essentially free
Quality Level 200 
storage temp. −20°C
type Type IV
Analysis Note: Where reported, agglutination activity is expressed in μg/ml and is determined from serial dilutions in phosphate buffered saline, pH 6.8, containing Ca2+ and Mn2+ of a 1 mg per mL solution. This activity is the lowest concentration to agglutinate a 2% suspension of human erythrocytes after 1 hr incubation at 25 °C.
Application: For the fluorescent detection of glycoproteins containing α−D-mannose or α−D-glucose
Biochem/physiol Actions: Con A is not blood group specific but has an affinity for terminal α-D-mannosyl and α-D-glucosyl residues. Ca2+ and Mn2+ ions are required for activity. Con A dissociates into dimers at pH 5.6 or below. Between pH 5.8 and pH 7.0, Con A exists as a tetramer; above pH 7.0 higher aggregates are formed. Con A exhibits mitogenic activity which is dependent on its degree of aggregation. Succinylation results in an active dimeric form which remains a dimer above pH 5.6.
Packaging: 2, 10 mg in glass bottle
Packaging: Package size based on protein content
Physical form: Lyophilized powder containing phosphate buffer salts and NaCl
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H317
Precautionary statements P280 - P302 + P352
Hazard Codes Xn
Risk Statements 42/43
Safety Statements 22-36/37-45
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Storage Temp. −20°C
UNSPSC 12352202

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