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Cefsulodin sodium salt hydrate

SIGMA/C8145 - third-generation cephalosporin antibiotic

Synonym: 7-(D-α-Sulfophenylacetamido)ceph-3-em-3-(4′-carbamoylpyridinium)methyl-4-carboxylate sodium salt

CAS Number: 52152-93-9
Empirical Formula (Hill Notation): C22H19N4NaO8S2 · xH2O
Molecular Weight: 554.53 (anhydrous basis)
EC Number: 257-692-4
MDL Number: MFCD07793338
Linear Formula: C22H19N4NaO8S2 · xH2O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-C8145-100MG 100 mg
 $74.20
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45-C8145-250MG 250 mg
 $119.00
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45-C8145-1G 1 g
 $368.00
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This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: C8145-1G

 

antibiotic activity spectrum Gram-negative bacteria
  Gram-positive bacteria
form powder or crystals
InChI 1S/C22H20N4O8S2.Na/c23-18(27)13-6-8-25(9-7-13)10-14-11-35-21-15(20(29)26(21)16(14)22(30)31)24-19(28)17(36(32,33)34)12-4-2-1-3-5-12;/h1-9,15,17,21H,10-11H2,(H4-,23,24,27,28,30,31,32,33,34);/q;+1/p-1/t15-,17-,21-;/m1./s1
InChI key REACMANCWHKJSM-DWBVFMGKSA-M
mode of action cell wall synthesis | interferes
Quality Level 200 
SMILES string [Na+].NC(=O)c1cc[n+](CC2=C(N3[C@H](SC2)[C@H](NC(=O)[C@@H](c4ccccc4)S([O-])(=O)=O)C3=O)C([O-])=O)cc1
storage temp. 2-8°C
Application: Cefsulodin is a third generation cephalosporin antibiotic that has very specific activity against Pseudomonas aeruginosa. Cefuslodin is used in CIN (cefsulodin-Irgasan-novobiocin) agar to select for microorganisms such as E. coli. Cefsulodin is a substrate for rat Oatp1a4. It has been used to study multidrug resistance-associated protein 4 in efflux transport of prostaglandin E2 across the mouse blood-brain barrier.
Application: Cefsulodin is used to study the effect of expression, binding, and inhibition of PBP1 and other penicillin-binding proteins (PBPs) on bacterial cell wall mucopeptide synthesis.
Biochem/physiol Actions: Cefsulodin is a cephalosporin. Cephalosporins disrupt cell wall synthesis by inhibiting PBP crosslinking of peptidoglycan.
General description: Chemical structure: ß-lactam
Other Notes: Keep container tightly closed in a dry and well-ventilated place.
Hazard Codes Xi
Risk Statements 36/37/38-42/43
Safety Statements 22-26-36/37-45
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. 2-8°C
UNSPSC 51284140

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