Anti-C-Reactive Protein antibody produced in goat
SIGMA/C8284 - whole antiserum
Synonym: Anti-CRP
MDL Number: MFCD00162183
Product Type: Chemical
Immunoelectrophoresis Human CRP serum (top round well) and Human purified CRP (bottom round well) was reacted with Anti-C-Reactive Protein antibody produced in Goat (Cat. No. C8284) (canel well) to detect C-Reactive Protein through precipitation arcs.
| antibody form | whole antiserum |
| antibody product type | primary antibodies |
| biological source | goat |
| clone | polyclonal |
| conjugate | unconjugated |
| contains | 15 mM sodium azide |
| Quality Level | 200  |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | Ouchterlony double diffusion: 1:16-1:32 |
| UniProt accession no. | P02741  |
| Application: | Anti-C-Reactive protein antibody has been used in: • immunoassay reproducibility and binding affinity investigation of CRP-anti-CRP interaction. • in-house ELISA assay to study the CRP levels in plasma sample. |
| Application: | Anti-C-Reactive Protein antibody produced in goat has been used in enzyme-linked immunosorbent assay (ELISA). It has also been used in immunoassay reproducibility and binding affinity investigation of CRP-anti-CRP interaction. |
| Application: | Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below. Enzyme-linked immunosorbent assay (1 paper) |
| Biochem/physiol Actions: | C-reactive protein (CRP) plays an important role to provide an enhanced clearance of inappropriate materials from the plasma, whether these are of extrinsic origin, such as microorganisms and their products or the autologous products of cell damage and death. It acts as a systemic biomarker of acute inflammation and tissue damage. |
| Biochem/physiol Actions: | Specificity for human CRP is determined by immunoelectrophoresis (IEP) versus human CRP positive serum and purified human CRP. No reactivity with normal human serum is observed. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | C-reactive protein (CRP) is a first acute-phase plasma protein. It is synthesized in the hepatocyte and the concentration increase during inflammatory states even chronic inflammation. It′s level can increase during inflammation by up to 100 or 500 times. |
| General description: | C-reactive protein is encoded by the gene mapped to human chromosome 1q23.2. |
| Physical form: | Goat Anti-Human CRP is supplied as a liquid containing 0.1% sodium azide (see MSDS) as preservative. |
| Preparation Note: | For continuous use, store at 2-8 °C for up to one month. For extended storage, the solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in "frost-free" freezers not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. |
| Hazard Codes | Xn |
| Risk Statements | 21/22 |
| Safety Statements | 36/37-60 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |