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Thiamine pyrophosphate

SIGMA/C8754 - ≥95%

Synonym: Aneurinepyrophosphoric acid; Cocarboxylase; Thiamine pyrophosphate chloride

CAS Number: 154-87-0
Empirical Formula (Hill Notation): C12H19ClN4O7P2S
Molecular Weight: 460.77
EC Number: 205-836-1
MDL Number: MFCD00038740
Linear Formula: C12H19ClN4O7P2S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-C8754-1G 1 g
 $62.10
1/EA		 Add To Favorites
45-C8754-5G 5 g
 $81.60
1/EA		 Add To Favorites
45-C8754-25G 25 g
 $331.00
1/EA		 Add To Favorites
45-C8754-100G 100 g
 $940.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: C8754-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: C8754-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: C8754-5G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: C8754-25G

 

assay ≥95%
form powder
InChI 1S/C12H18N4O7P2S.ClH/c1-8-11(3-4-22-25(20,21)23-24(17,18)19)26-7-16(8)6-10-5-14-9(2)15-12(10)13;/h5,7H,3-4,6H2,1-2H3,(H4-,13,14,15,17,18,19,20,21);1H
InChI key YXVCLPJQTZXJLH-UHFFFAOYSA-N
Quality Level 200 
SMILES string CC1=C(CCOP(OP(O)(O)=O)(O)=O)SC=[N+]1CC2=C(N)N=C(C)N=C2.[Cl-]
solubility H2O: soluble 50 mg/mL, clear to very slightly hazy, colorless
storage temp. −20°C
Application: Thiamine pyrophosphate from Sigma has been used as a substrate to assay the enzymes in golgi lamellae isolated from rat tissue.
Application: Thiamine pyrophosphate has been used:
• for the preparation of chitosan nano-particles
• as a standard for vitamin B1 and its derivative in high-performance
• liquid chromatography (HPLC) analysis
• immunofluorescence
Biochem/physiol Actions: Thiamine pyrophosphate (TPP) is a coenzyme of transketolase, that catalyzes the cleavage of ribulose-5-phosphate. This reaction leads to the formation of D-glyceraldehyde-3-phosphate. It requires the addition of an acceptor aldehyde such as ribose-5-phosphate, glyceraldehye or glycolaldehyde. TPP is capable of decarboxylating hydroxypyruvate in the presence of an ′acceptor aldehyde′.
Packaging: 1, 5, 25, 100 g in poly bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥95%
Storage Temp. −20°C
UNSPSC 12352204

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