β-Chloro-L-alanine hydrochloride

SIGMA/C9033 - Alanine aminotransferase inhibitor

Synonym: (R)-2-Amino-3-chloropropanoic acid; 3-Chloro-L-alanine

CAS Number: 51887-89-9
Empirical Formula (Hill Notation): C₃H₆ClNO₂ · HCl
Molecular Weight: 160.00
MDL Number: MFCD00070398
Linear Formula: C₃H₆ClNO₂ · HCl
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-C9033-250MG	250 mg	$324.00 1/EA		Add To Favorites
45-C9033-5G	5 g	$2020.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (TLC)
biological source	synthetic
form	powder
InChI	1S/C3H6ClNO2.ClH/c4-1-2(5)3(6)7;/h2H,1,5H2,(H,6,7);1H/t2-;/m0./s1
InChI key	IENJPSDBNBGIEL-DKWTVANSSA-N
mp	205 °C
Quality Level	200
SMILES string	Cl[H].N[C@@H](CCl)C(O)=O
solubility	water: 50 mg/mL, clear, colorless
storage temp.	−20°C

Application:	β-Chloro-L-alanine hydrochloride has been used: • as a substrate for screening tyrosine phenol lyase steady state kinetics • in the inhibition of serine palmitoyltransferase and cytotoxicity studies in lymphocyte Ly-1 cells • as an inhibitor of alanine transaminase in wheat germ cell-free protein synthesis system
Biochem/physiol Actions:	β-Chloro-L-alanine hydrochloride is an inhibitor of alanine aminotransferase (ALAT). Inhibition of ALAT leads to suppression of tumor progression in lung carcinoma.

Symbol	GHS07
Signal word	Warning
Hazard statements	H315 - H319 - H335
Precautionary statements	P302 + P352 - P305 + P351 + P338
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (TLC)
mp	205 °C
Storage Temp.	−20°C
UNSPSC	12352204

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