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Calcium Ionophore A23187 hemicalcium salt

SIGMA/C9275 - powder

Synonym: A23187 hemicalcium salt; Antibiotic A 23187 hemicalcium salt; Calcimycin hemicalcium salt; Calimycin hemicalcium salt

CAS Number: 59450-89-4
Empirical Formula (Hill Notation): C29H36Ca0.5N3O6
Molecular Weight: 542.65
MDL Number: MFCD00077678
Linear Formula: C29H36Ca0.5N3O6
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-C9275-1MG 1 mg
 $164.00
1/EA		 Add To Favorites
45-C9275-5MG 5 mg
 $540.00
1/EA		 Add To Favorites

 

antibiotic activity spectrum fungi
  Gram-positive bacteria
color yellow
form powder
InChI 1S/2C29H37N3O6.Ca/c2*1-15-10-11-29(17(3)13-16(2)27(38-29)18(4)26(33)20-7-6-12-31-20)37-22(15)14-23-32-25-21(36-23)9-8-19(30-5)24(25)28(34)35;/h2*6-9,12,15-18,22,27,30-31H,10-11,13-14H2,1-5H3,(H,34,35);/q;;+2/p-2/t15-,16-,17-,18-,22-,27+,29?;15-,16-,17-,18-,22-,27+,29+;/m11./s1
InChI key LAQWEYASNNRUGY-PLYBNSMSSA-L
mode of action cell membrane | interferes
Quality Level 200 
SMILES string CNc1ccc2oc(C[C@H]3O[C@@]4(CC[C@H]3C)O[C@@H]([C@H](C)C[C@H]4C)[C@H](C)C(=O)c5ccc[nH]5)nc2c1C(=O)O[Ca]OC(=O)c6c(NC)ccc7oc(C[C@H]8O[C@@]9(CC[C@H]8C)O[C@@H]([C@H](C)C[C@H]9C)[C@H](C)C(=O)c%10ccc[nH]%10)nc67
solubility DMSO: soluble
  ethanol: soluble
sterility non-sterile
storage temp. 2-8°C
Application: Ionophore highly selective for Ca2+. Potentiates responses to NMDA but not quisqualate. In cell culture, stimulates nitric oxide production by calmodulin-dependent constitutive nitric oxide synthase.
Application: Ionophore highly selective for Ca2+. Stimulates nitric oxide production in cells by calmodulin-dependent constitutive nitric oxide synthase.
Packaging: 1, 5, 10 mg in glass bottle
Storage Temp. 2-8°C
UNSPSC 12352200

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