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Calcium Ionophore A23187 hemimagnesium salt

SIGMA/C9400

Synonym: A23187 hemimagnesium salt; Antibiotic A 23187 hemimagnesium salt; Calcimycin hemimagnesium salt; Calimycin hemimagnesium salt

CAS Number: 72124-77-7
Empirical Formula (Hill Notation): C29H36Mg0.5N3O6
Molecular Weight: 534.77
MDL Number: MFCD00151203
Linear Formula: C29H36Mg0.5N3O6
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-C9400-5MG 5 mg
 $424.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: C9400-10MG

 

antibiotic activity spectrum fungi
  Gram-positive bacteria
form powder
InChI 1S/2C29H37N3O6.Mg/c2*1-15-10-11-29(17(3)13-16(2)27(38-29)18(4)26(33)20-7-6-12-31-20)37-22(15)14-23-32-25-21(36-23)9-8-19(30-5)24(25)28(34)35;/h2*6-9,12,15-18,22,27,30-31H,10-11,13-14H2,1-5H3,(H,34,35);/q;;+2/p-2/t2*15-,16-,17-,18-,22-,27+,29+;/m11./s1
InChI key XBWKBTZDBYFEMH-UIOMRPQBSA-L
mode of action cell membrane | interferes
Quality Level 200 
SMILES string CNc1ccc2oc(C[C@H]3O[C@@]4(CC[C@H]3C)O[C@@H]([C@H](C)C[C@H]4C)[C@H](C)C(=O)c5ccc[nH]5)nc2c1C(=O)O[Mg]OC(=O)c6c(NC)ccc7oc(C[C@H]8O[C@@]9(CC[C@H]8C)O[C@@H]([C@H](C)C[C@H]9C)[C@H](C)C(=O)c%10ccc[nH]%10)nc67
sterility non-sterile
storage temp. 2-8°C
Application: Ionophore highly selective for Ca2+. Potentiates responses to NMDA but not quisqualate. In cell culture, stimulates nitric oxide production by calmodulin-dependent constitutive nitric oxide synthase. Used to study effects of elevated intracellular calcium on mitochondrial function and intrinsic apoptosis.
Packaging: 5, 10 mg in glass bottle
Storage Temp. 2-8°C
UNSPSC 12352202

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