CHAPS hydrate
SIGMA/C9426 - BioReagent, suitable for electrophoresis, ≥98% (HPLC)
Synonym: 3-
CAS Number: 331717-45-4
Empirical Formula (Hill Notation): C32H58N2O7S · xH2O
Molecular Weight: 614.88 (anhydrous basis)
MDL Number: MFCD00012116
Linear Formula: C32H58N2O7S · xH2O
Product Type: Chemical
| assay | ≥98% (HPLC) |
| description | zwitterionic |
| form | powder |
| impurities | <0.04% DMF |
| InChI | 1S/C32H58N2O7S.H2O/c1-21( |
| InChI key | SJCUTFKCLFLIFE-JWTJKVBLSA |
| mol wt | 614.88 g/mol (anhydrous basis) |
| mp | 157 °C (dec.) (lit.) |
| product line | BioReagent |
| Quality Level | 200 ![]() |
| SMILES string | O.C[C@H](CCC(=O)NCCC[N+]( |
| solubility | water: 50 mg/mL, clear, colorless |
| storage temp. | room temp |
| suitability | suitable for electrophoresis |
| technique(s) | electrophoresis: suitable |
| protein quantification: suitable |
| Application: | CHAPS has been used: • For membrane permeabilization of cells • As a component in lysis buffer for homogenization of liver tissues as well as adipose tissue • As a component in denaturing buffer in enzyme characterization • As a component of 2D- sample buffer in 2D electrophoresis • For protein solubilization in isoelectric focusing |
| General description: | CHAPS is a non-denaturing, zwitterionic sulfobetaine detergent. It is mild and solubilizes membrane proteins and receptors. It is useful for breaking protein-protein interactions. It is a derivative of the naturally occurring bile salts. It has small micellar molecular weight (6,150) and high critical micellar concentration (6 - 10 mM) allowing it to be removed from samples by dialysis. |
| Packaging: | 1, 5 g in glass bottle |
| Symbol | GHS08 |
| Signal word | Danger |
| Hazard statements | H360D |
| Precautionary statements | P201 - P202 - P280 - P308 + P313 - P405 - P501 |
| Hazard Codes | T |
| Risk Statements | 61-36/37/38 |
| Safety Statements | 53-22-26-35-36/37 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| mp | 157 °C (dec.) (lit.) |
| Storage Temp. | room temp |
| UNSPSC | 12161902 |


