Complement Serum Standard human
SIGMA/C9473 - aqueous solution
Synonym: Human Complement Serum
Product Type: Chemical
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| application(s) | cell analysis |
| biological source | human |
| form | aqueous solution |
| Quality Level | 200  |
| shipped in | dry ice |
| storage temp. | −70°C |
| Application: | Complement Serum Standard human has been used as a positive control to study the role of the complement system in immunological demyelination of the spinal cord from mammals. |
| Biochem/physiol Actions: | The complement system is an important constituent of innate immunity. It participates in the first line of defense against microbial infections, altered host cells, and removal of immune complexes and injured cells. The complement system comprises more than thirty components such as the plasma proteins produced by the liver, membrane proteins expressed on the cell surface, cytokines, and hormones. The complement proteins come together to opsonize the pathogens and initiate a cascade of inflammatory responses serving the immune cells to fight the infection and maintain homeostasis. |
| Disclaimer: | RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization. |
| General description: | The complement serum standard human is suitable for the determination of CH50 and AP50 complement activities. This allows for a test of the complement activity on the capacity of the serum to lyse red blood cells in vitro and can be used in procedures for genotyping DNA samples of the complement system. |
| Physical form: | Supplied as a 0.22 μm filtered solution containing ~ 18 mM citrate, ~22 mM dextrose, ~3 mM phosphate and ~13 mM calcium |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −70°C |
| UNSPSC | 12352202 |