Monoclonal Anti-Calcitonin Gene-Related Peptide antibody produced in mouse
SIGMA/C9487 - clone CD8, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-CGRP
MDL Number: MFCD00162203
Product Type: Chemical
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| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | CD8, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| isotype | IgG1 |
| Quality Level | 200  |
| shipped in | dry ice |
| species reactivity | guinea pig, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunocytochemistry: suitable |
| immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:200-1:1,000 using ovenight incubation at 4 °C and sections that have been protease-digested or processed by high temperature antigen retrieval | |
| indirect immunofluorescence: 1:500 using overnight incubation at 4 °C | |
| UniProt accession no. | P01258  |
| Application: | Anti-Calcitonin Gene-Related Peptide (CGRP) antibody is suitable for immunohistochemistry at a working antibody dilution of 1:200 to 1:1000 using formalin-fixed, paraffin-embedded sections or cryostat tissue sections. The antibody may be used for immunofluorescence at a working dilution of 1:500. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Calcitonin gene-related peptide (CGRP) is a vasodilator that belongs to the calcitonin family of peptides. It is produced by motor neurons of peripheral and central nervous system. There are two forms of CGRP, α and β, which exhibit similar functions. The effects of CGRP are mediated by G-protein coupled receptor heterodimer formed by calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifyi Monoclonal Anti-Calcitonin Gene-Related Peptide (CGRP) recognizes human and guinea pig CGRP. It does not cross react with rat CGRP. |
| Immunogen: | peptide corresponding to the C-terminal of rat α−calcitonin gene-related peptite (CGRP). |
| Physical form: | Solution in PBS containing 1% BSA and ≤ 0.1% sodium azide |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |