L-Carnosine

SIGMA/C9625 - ~99%, crystalline

Synonym: β-Alanyl-L-histidine

CAS Number: 305-84-0
Empirical Formula (Hill Notation): C₉H₁₄N₄O₃
Molecular Weight: 226.23
EC Number: 206-169-9
MDL Number: MFCD00005207
Linear Formula: C₉H₁₄N₄O₃
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-C9625-10MG	10 mg	$29.90 1/EA	Add To Favorites
45-C9625-5G	5 g	$152.00 1/EA	Add To Favorites
45-C9625-25G	25 g	$571.00 1/EA	Add To Favorites
45-C9625-100G	100 g	$2000.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: C9625-25G

Properties
Descriptions
Safety Info.
Basic Data

application(s)	cell analysis
assay	~99%
color	white to off-white
form	crystalline
InChI	1S/C9H14N4O3/c10-2-1-8(14)13-7(9(15)16)3-6-4-11-5-12-6/h4-5,7H,1-3,10H2,(H,11,12)(H,13,14)(H,15,16)/t7-/m0/s1
InChI key	CQOVPNPJLQNMDC-ZETCQYMHSA-N
mp	253 °C (dec.) (lit.)
Quality Level	200
SMILES string	NCCC(=O)N[C@@H](Cc1c[nH]cn1)C(O)=O
storage temp.	−20°C

Amino Acid Sequence:	Ala-His
Application:	L-Carnosine has been used to study its effects as an antioxidant on meat quality of pigs. It has also been used to study its effects on brain injury in a rat intracerebral hemorrhage model.
Biochem/physiol Actions:	L-Carosine is a dipeptide found at millimolar concentration in brain, muscle and the lens of the eye. In model systems it is a potent antioxidant that scavenges oxygen free radicals and transition metal ions. It blocks protein-protein and protein-DNA cross-links induced by hypochlorite anions and toxic aldehydes such as acetaldehyde, formaldehyde, and malondialdehyde, the primary product of lipid peroxidation. It also inhibits nonenzymatic protein glycation induced by aldose and ketose reducing sugars and inhibits the formation of toxic advanced glycation end products (AGE). These activities make it of interest in studies of aging, atherosclerosis, Alzheimer′s disease, and the secondary effects of diabetes.
Biochem/physiol Actions:	Dipeptide with potent antioxidant and antiglycation activity; blocks nonenzymatic glycosylation and protein cross-linking induced by reactive aldehydes.
Packaging:	10 mg in poly bottle
Packaging:	5, 25, 100 g in poly bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	~99%
mp	253 °C (dec.) (lit.)
Storage Temp.	−20°C
UNSPSC	12352209

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