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β-Carotene

SIGMA/C9750 - synthetic, ≥93% (UV), powder

Synonym: β,β-Carotene; Provitamin A

CAS Number: 7235-40-7
Empirical Formula (Hill Notation): C40H56
Molecular Weight: 536.87
EC Number: 230-636-6
MDL Number: MFCD00001556
Linear Formula: C40H56
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-C9750-5G 5 g
$79.10
1/EA
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45-C9750-10G 10 g
$156.00
1/EA
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: C9750-10G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: C9750-5G

 

assay ≥93% (UV)
biological source synthetic
color dark red to brown
form powder
InChI 1S/C40H56/c1-31(19-13-21-33(3)25-27-37-35(5)23-15-29-39(37,7)8)17-11-12-18-32(2)20-14-22-34(4)26-28-38-36(6)24-16-30-40(38,9)10/h11-14,17-22,25-28H,15-16,23-24,29-30H2,1-10H3/b12-11+,19-13+,20-14+,27-25+,28-26+,31-17+,32-18+,33-21+,34-22+
InChI key OENHQHLEOONYIE-JLTXGRSLSA-N
mp 178-179 °C
potency ~1,600,000 units vitamin A per g
Quality Level 200 
SMILES string CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)CCCC2(C)C)C(C)(C)CCC1
solubility DMSO: 30 μg/mL
  hexane: 1.1 mg/mL
storage temp. −20°C
Application: β-carotene has been used:
• to generate nano emulsions to evaluate their bioavailability potential
• as a standard, for β-carotene evaluation in blood and skin samples using high performance liquid chromatography (HPLC),
• as a dietary supplement of vitamin-A in young rats by HPLC
• as a dietary supplement in mice to reduce hearing loss and hair cell damage

Biochem/physiol Actions: The most important of the provitamins A, β-carotene can be classified as an antioxidant due to its inhibition of radical initiated peroxidation in vitro. However, in vivo it appears to act either as an antioxidant or a prooxidant depending on cellular environment. It reduces the incidence of many cancers, but enhances lung cancer incidence in smokers.
Biochem/physiol Actions: The most important of the provitamins A.
Disclaimer: Purchase minimum quantity required. Discard one month after opening.
General description: Carotenoids are an important class of naturally occurring pigments found in fruits and vegetables. Among the carotenoids, β-carotene has the greatest provitamin A potential and functions to reduce the risk of cancer, cardiovascular diseases and macular degeneration. Low water solubility and poor chemical stability attributes to low absorption of β-carotene from food. β-carotene along with digestible lipids enriches its bio accessibility. Emulsions or nano emulsions encapsulates effectively delivers lipophilic β-carotene and increases its bioavailability. β-carotene has anti-oxidant potential and reduces noise induced hearing loss and progression of macular degeneration.
Packaging: 5, 10, 25 g in glass bottle
Packaging: Packaged in serum vials.
Risk Statements 44
Safety Statements 7-15-18
RIDADR NONH for all modes of transport
WGK Germany WGK 1
Flash Point(F) 217.9 °F - closed cup
Flash Point(C) 103.3 °C - closed cup
Purity ≥93% (UV)
mp 178-179 °C
Storage Temp. −20°C
UNSPSC 12352205

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