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Cyclothiazide

SIGMA/C9847

Synonym: 6-Chloro-3,4-dihydro-3-(2-norbornen-5-yl)-2H-1,2-4-benzothiadiazine-7-sulfonamide 1,1-dioxide

CAS Number: 2259-96-3
Empirical Formula (Hill Notation): C14H16ClN3O4S2
Molecular Weight: 389.88
EC Number: 218-859-7
MDL Number: MFCD00210192
Linear Formula: C14H16ClN3O4S2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-C9847-10MG 10 mg
 $126.00
1/EA		 Add To Favorites
45-C9847-25MG 25 mg
 $301.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: C9847-25MG

 

form powder
InChI 1S/C14H16ClN3O4S2/c15-10-5-11-13(6-12(10)23(16,19)20)24(21,22)18-14(17-11)9-4-7-1-2-8(9)3-7/h1-2,5-9,14,17-18H,3-4H2,(H2,16,19,20)/t7-,8+,9?,14?/m0/s1
InChI key BOCUKUHCLICSIY-QJWLJZLASA-N
originator Eli Lilly
Quality Level 200 
SMILES string [H][C@@]12CC(C3Nc4cc(Cl)c(cc4S(=O)(=O)N3)S(N)(=O)=O)[C@@]([H])(C1)C=C2
storage temp. 2-8°C
Application: Cyclothiazide has been used as a α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) desensitization blocker to study the effects of γ2 on receptor desensitization.
Biochem/physiol Actions: Blocks the rapid desensitization of the AMPA glutamate receptors and markedly prolongs the decay time of the evoked excitatory post-synaptic current.
Features and Benefits: This compound is a featured product for Neuroscience research. Click here  to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Features and Benefits: This compound is featured on the Glutamate Receptors (Ion Channel Family)  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Features and Benefits: This compound was developed by Eli Lilly . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
General description: Cyclothiazide is a benzothiadiazine, which has a similar structure to diazoxide.
Packaging: 10 mg in poly bottle
Packaging: 25 mg in glass bottle
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
RIDADR NONH for all modes of transport
WGK Germany WGK 2
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. 2-8°C
UNSPSC 12352125

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