Glutathione-S-Transferase (GST) Assay Kit
SIGMA/CS0410 - sufficient for 500 multiwell tests
Synonym: GST Enzyme Activity Kit
EC Number: 202-551-4
Product Type: Chemical
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Unit Definition One unit will conjugate 1.0 μmole of 1-chloro-2,4-dinitrobenzene with reduced glutathione per min at pH 6.5 at 25°C.
| Quality Level | 200  |
| shipped in | dry ice |
| storage temp. | −20°C |
| usage | sufficient for 500 multiwell tests |
| Application: | The Glutathione S-Transferase Assay kit utilizes 1-Chloro-2,4-dinitrobenze |
| Biochem/physiol Actions: | Glutathione S-transferases (GSTs) are a group of enzymes important in the detoxification of many xenobiotics in mammals. The enzymes protect cells against toxicants by conjugating the thiol group of the glutathione to electrophilic xenobiotics, and thereby defend cells against the mutagenic, carcinogenic, and toxic effects of the compounds. GST activity is present in plants, insects, yeast, bacteria, and most mammalian tissues especially in the liver, which plays a key role in detoxification. |
| General description: | The Glutathione S-Transferase (GST) Assay Kit is designed to measure total GSTactivity. It can be used to measure GST activity in cell and bacterial lysates, tissue homogenates, and in plasma and erythrocyte lysates |
| Symbol |    GHS05,GHS06,GHS09 |
| Signal word | Danger |
| Hazard statements | H302 - H310 - H315 - H317 - H318 - H410 |
| Precautionary statements | P262 - P273 - P280 - P301 + P312 - P302 + P352 + P310 - P305 + P351 + P338 |
| Hazard Codes | T,N |
| Risk Statements | 23/24/25-33-38-41-43-50/53 |
| Safety Statements | 24-28-36/37-45-60-61 |
| RIDADR | UN 3316 9 |
| WGK Germany | WGK 2 |
| Flash Point(F) | 381.2 °F - closed cup |
| Flash Point(C) | 194 °C - closed cup |
| Storage Temp. | −20°C |
| UNSPSC | 12161503 |
| Components | Dulbecco's Phosphate Buffered Saline 100 mL; L-Glutathione Reduced 1 g; GST (Control) .1 mL; Sample Buffer 5 mL; Substrate (CDNB) 1.2 mL |