Deoxynivalenol
SIGMA/D0156
Synonym: 3α,7α,15-Trihydroxy-12,13-epoxytrichothec-9-en-8-one; Vomitoxin
CAS Number: 51481-10-8
Empirical Formula (Hill Notation): C15H20O6
Molecular Weight: 296.32
MDL Number: MFCD09039270
Linear Formula: C15H20O6
Product Type: Chemical
| form | powder |
| InChI | 1S/C15H20O6/c1-7-3-9-14(5 |
| InChI key | LINOMUASTDIRTM-QGRHZQQGSA |
| Quality Level | 300 ![]() |
| SMILES string | [H][C@]12O[C@]3([H])[C@H] |
| storage temp. | 2-8°C |
| Application: | Deoxynivalenol has been used: • as a mycotoxin to induce cytotoxicity in porcine jejunal epithelial cells and study the protective effects of Saccharomyces cerevisiae on the cell viability of host cells. • to induce toxicity in nude mice to study the effect of probiotics (Lactobacillus rhamnosus GG (LGG) or Lactobacillus acidophilus (LA)) supplementation on host protection • as a thyroid hormone receptor (TRβ) antagonist in cell-based luciferase reporter gene (CALUX) assay |
| Biochem/physiol Actions: | Deoxynivalenol (DON) blocks the synthesis of DNA and RNA by inhibiting the process of translation. |
| General description: | Deoxynivalenol (DON) is a natural mycotoxin found in Fusarium graminearum and Fusarium culmorum. It belongs to the B-trichothecenes family of mycotoxins. |
| Packaging: | 1, 5 mg in serum bottle |
| Symbol | GHS06 |
| Signal word | Danger |
| Hazard statements | H300 |
| Precautionary statements | P264 - P270 - P301 + P310 - P405 - P501 |
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 36/37/39-45 |
| RIDADR | UN 2811 6.1 / PGII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |


