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Dobutamine hydrochloride

SIGMA/D0676 - ≥98%

Synonym: (±)-3,4-Dihydroxy-N-[3-(4-hydroxyphenyl)-1-methylpropyl]-β-phenethylamine hydrochloride

CAS Number: 49745-95-1
Empirical Formula (Hill Notation): C18H23NO3 · HCl
Molecular Weight: 337.84
EC Number: 256-464-1
MDL Number: MFCD00153795
Linear Formula: C18H23NO3 · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-D0676-10MG 10 mg
 $87.10
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45-D0676-50MG 50 mg
 $279.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D0676-50MG

 

assay ≥98%
form powder
InChI 1S/C18H23NO3.ClH/c1-13(2-3-14-4-7-16(20)8-5-14)19-11-10-15-6-9-17(21)18(22)12-15;/h4-9,12-13,19-22H,2-3,10-11H2,1H3;1H
InChI key BQKADKWNRWCIJL-UHFFFAOYSA-N
originator Eli Lilly
Quality Level 200 
SMILES string Cl[H].CC(CCc1ccc(O)cc1)NCCc2ccc(O)c(O)c2
storage temp. 2-8°C
Application: Dobutamine hydrochloride has been used:
• to treat mouse embryonic fibroblasts for cell death analysis
•  to inhibit TAZ (transcriptional coactivator with PDZ-binding motif)/YAP (Yes-associated protein) of Hippo pathway and study its effect on tumor cell proliferation
•  as β1-AR partial agonist to determine its effects on budding of endophilin-mRFP-positive structures by live-cell imaging
Biochem/physiol Actions: Dobutamine is a synthetic catecholamine that stimulate the β1 -adrenoceptor receptor. It exhibits inotropic outcome on the myocardium. Dobutamine elevates contractility and is known to be useful in the condition of low blood pressure.
Features and Benefits: This compound was developed by Eli Lilly . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Purity ≥98%
Storage Temp. 2-8°C
UNSPSC 12352116

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