Diazepam
SIGMA/D0899
Synonym: 7-
CAS Number: 439-14-5
Empirical Formula (Hill Notation): C16H13ClN2O
Molecular Weight: 284.74
EC Number: 207-122-5
MDL Number: MFCD00057323
Linear Formula: C16H13ClN2O
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D0899-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D0899-1G
| drug control | kontrollierte Droge in Deutschland |
| USDEA Schedule IV; Home Office Schedule 4.1; psychotrope (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal); Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet | |
| form | powder |
| InChI | 1S/C16H13ClN2O/c1-19-14-8 |
| InChI key | AAOVKJBEBIDNHE-UHFFFAOYSA |
| originator | Roche |
| Quality Level | 200  |
| SMILES string | CN1C(=O)CN=C(c2ccccc2)c3c |
| solubility | 45% (w/v) aq 2-hydroxypropyl-β-cyclode |
| DMF: soluble | |
| ethanol: soluble | |
| H2O: slightly soluble |
| Application: | Diazepam has been used: • as an anxiolyte in pilocarpine protocol. • in multi-electrode array (MEA) technology • as a marker for human serum albumin |
| Biochem/physiol Actions: | Anxiolytic; ligand for the GABAA receptor benzodiazepine modulatory site. |
| Biochem/physiol Actions: | Diazepam is a benzodiazepine anxiolytic agent. It serves as a prototype ligand for the GABAA receptor benzodiazepine modulatory site. |
| Biochem/physiol Actions: | Diazepam is often used as a sedative. Its metabolism involves cytochrome P450 (CYP) 2C19 and 3A4. Diazepam has immediate action upon administration. |
| Features and Benefits: | This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm . |
| Features and Benefits: | This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Features and Benefits: | This compound was developed by Roche . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| Legal Information: | German Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG. English This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies. |
| Symbol |   GHS06,GHS09 |
| Signal word | Danger |
| Hazard statements | H301 + H311 - H410 |
| Precautionary statements | P273 - P280 - P301 + P310 + P330 - P302 + P352 + P312 |
| Hazard Codes | Xn |
| Risk Statements | 21/22 |
| Safety Statements | 36/37 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| UNSPSC | 12352200 |