Dihydrokainic acid
SIGMA/D1064 - ≥98% (HPLC), powder
Synonym: 2-
CAS Number: 52497-36-6
Empirical Formula (Hill Notation): C10H17NO4
Molecular Weight: 215.25
MDL Number: MFCD03412037
Linear Formula: C10H17NO4
Product Type: Chemical
| assay | ≥98% (HPLC) |
| form | powder |
| InChI | 1S/C10H17NO4/c1-5(2)7-4-1 |
| InChI key | JQPDCKOQOOQUSC-OOZYFLPDSA |
| Quality Level | 100  |
| SMILES string | CC(C)[C@H]1CN[C@@H]([C@H] |
| solubility | H2O: >10 mg/mL |
| storage temp. | 2-8°C |
| Application: | Dihydrokainic acid has been used as a glutamate transporter (GLT-1) inhibitor in the glutamate uptake assay of astrocytes and glial cells. It may be used as a GLT-1 inhibitor in Lateral habenula (LHb). |
| Biochem/physiol Actions: | Dihydrokainic acid is a selective GLT-1 glutamate transporter inhibitor; weak inhibitor of AMPA/kainate glutamic acid receptors at high concentrations. |
| Biochem/physiol Actions: | Dihydrokainic acid is a selective inhibitor of the GLT-1 glutamate transporter. At higher concentrations, dihydrokainate is a weak inhibitor of AMPA/kainate glutamic acid receptors. |
| Biochem/physiol Actions: | Dihydrokainic favors neuronal cell death. It modulates anxiety and depression behaviors. |
| Features and Benefits: | This compound is featured on the Excitatory Amino Acid Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Packaging: | 10, 50 mg in glass bottle |
| Hazard Codes | Xn |
| Risk Statements | 20/21/22 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352106 |