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DCB

SIGMA/D1068 - ≥98% (HPLC), solid

Synonym: 3,3′-Dichlorobenzaldazine; NSC 67224

CAS Number: 6971-97-7
Empirical Formula (Hill Notation): C14H10Cl2N2
Molecular Weight: 277.15
MDL Number: MFCD00556081
Linear Formula: C14H10Cl2N2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-D1068-10MG 10 mg
 $124.00
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45-D1068-50MG 50 mg
 $332.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D1068-50MG

 

assay ≥98% (HPLC)
color yellow
form solid
InChI 1S/C14H10Cl2N2/c15-13-5-1-3-11(7-13)9-17-18-10-12-4-2-6-14(16)8-12/h1-10H/b17-9+,18-10+
InChI key XMOVWXSCYLINBJ-BEQMOXJMSA-N
Quality Level 100 
SMILES string Clc1cccc(C=NN=Cc2cccc(Cl)c2)c1
solubility DMSO: ~6.8 mg/mL
  H2O: insoluble
storage condition desiccated
  under inert gas
storage temp. 2-8°C
Biochem/physiol Actions: 3,3′-dichlorobenzaldazine (DCB) serves as an allosteric ligand with neutral cooperativity. It helps to block the positive allosteric regulation of mGluRs (metabotropic glutamate receptor subtype 5 (mGluR5) with the help of 3,3′-difluorobenzaldazine (DFB) and the negative modulatory effect of 3,3′-dimethoxybenzaldazine (DMeOB).
Biochem/physiol Actions: Neutral allosteric modulator of the metabotropic glutamate receptor mGluR5.
Features and Benefits: This compound is featured on the Glutamate Receptors (G Protein Family)  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging: 10, 50 mg in glass bottle
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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