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Diosgenin

SIGMA/D1634 - ≥93%

Synonym: (25R)-5-Spirosten-3β-ol; 3β-Hydroxy-5-spirostene; Nitogenin

CAS Number: 512-04-9
Empirical Formula (Hill Notation): C27H42O3
Molecular Weight: 414.62
EC Number: 208-134-3
MDL Number: MFCD00016887
Linear Formula: C27H42O3
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-D1634-5G 5 g
 $75.40
1/EA		 Add To Favorites
45-D1634-100G 100 g
 $832.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D1634-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D1634-5G

 

assay ≥93%
form powder
InChI 1S/C27H42O3/c1-16-7-12-27(29-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(28)8-10-25(18,3)21(20)9-11-26(22,24)4/h5,16-17,19-24,28H,6-15H2,1-4H3/t16-,17+,19+,20-,21+,22+,23+,24+,25+,26+,27-/m1/s1
InChI key WQLVFSAGQJTQCK-VKROHFNGSA-N
Quality Level 200 
SMILES string [H][C@]12C[C@@]3([H])[C@]4([H])CC=C5C[C@@H](O)CC[C@]5(C)[C@@]4([H])CC[C@]3(C)[C@@]1([H])[C@H](C)[C@@]6(CC[C@@H](C)CO6)O2
Application: Diosgenin has been:
• used as a standard in the analysis of total saponins in Sapindus rarak
• orally administered to the rats to study its role against atherogenic diet-induced production of inflammatory mediators in heart, liver and brain
• used as a standard compound to determine the saponins content in chickpea and Tribulus terrestris
Biochem/physiol Actions: Diosgenin induces apoptosis in colon cancer cell lines and induces apoptosis, cell cycle arrest and cyclooxygenase activity in osteosarcoma cells. It serves as a precursor in steroid drug production. Diosgenin is shown to promote cholesterol production by stimulating biliary excretion. It influences lipoxygenase induced human erythroleukemia cell line differentiation.
General description: Diosgenin is a triterpene and a glycone derivative of dioscin. Yams, Trigonella foenum-graecum and Costus speciosus are some of its source.
Packaging: 5, 100 g in poly bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 2
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥93%
UNSPSC 12352200

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