5′-Deoxyadenosine
SIGMA/D1771 - methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase substrate
Synonym: 5′-dAdo
CAS Number: 4754-39-6
Empirical Formula (Hill Notation): C10H13N5O3
Molecular Weight: 251.24
MDL Number: MFCD00056003
Linear Formula: C10H13N5O3
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D1771-25MG
| assay | ≥98% (TLC) |
| biological source | synthetic (organic) |
| form | powder |
| InChI | 1S/C10H13N5O3/c1-4-6(16)7 |
| InChI key | XGYIMTFOTBMPFP-KQYNXXCUSA |
| Quality Level | 200  |
| SMILES string | C[C@H]1O[C@H]([C@H](O)[C@ |
| solubility | hot water: 19.60-20.40 mg/mL, clear, colorless |
| storage temp. | 2-8°C |
| Application: | 5′-Deoxyadenosine has been used: • as a standard in mass spectroscopy • as an inhibitor for screening thymidine phosphorylase activity • as a substrate in 5′-Deoxyadenosine deaminase (DadD) assay |
| Biochem/physiol Actions: | 5′-Deoxyadenosine is a substrate for the enzyme methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase in microbes. 5′-Deoxyadenosine is a byproduct of cleavage of S-adenosylmethionine (SAM). High levels of 5′-Deoxyadenosine inhibits SAM dependent enzymes. It also inhibits biotin synthase (BioB) and lipoyl synthase (LipA) enzymes. |
| Packaging: | 25 mg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (TLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 41106305 |