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Dexamethasone 21-acetate

SIGMA/D1881 - ≥99%

Synonym: 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione-21-acetate; 9α-Fluoro-16α-methylprednisolone-21-acetate; Prednisolone F acetate

CAS Number: 1177-87-3
Empirical Formula (Hill Notation): C24H31FO6
Molecular Weight: 434.50
EC Number: 214-646-8
MDL Number: MFCD00027407
Linear Formula: C24H31FO6
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-D1881-100MG 100 mg
 $66.60
1/EA		 Add To Favorites
45-D1881-500MG 500 mg
 $197.00
1/EA		 Add To Favorites
45-D1881-1G 1 g
 $352.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D1881-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D1881-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D1881-500MG

 

assay ≥99%
form powder
InChI 1S/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17+,18+,19+,21+,22+,23+,24+/m1/s1
InChI key AKUJBENLRBOFTD-RPRRAYFGSA-N
Quality Level 100 
SMILES string [H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@@H](C)[C@]4(O)C(=O)COC(C)=O
storage temp. 2-8°C
Application: Dexamethasone 21-acetate has been used:
• as a component of the induction medium for the treatment of mice preadipocytes (5A) cells
• as a synthetic glucocorticoid to study its effects on the expression of nuclear factor erythroid 2-related factor 2 (Nrf2) and peroxiredoxin 6 (Prdx6) proteins in placentas of human and mice
• as a component of the complete medium for the culturing of porcine hepatocytes

Biochem/physiol Actions: Dexamethasone 21-acetate or dexamethasone acetate is a derivative of dexamethasone. It is a hydrophobic drug. Dexamethasone is a glucocorticoid possessing anti-inflammatory activity.
Packaging: 1 g in poly bottle
Packaging: 100, 500 mg in poly bottle
Purity ≥99%
Storage Temp. 2-8°C
UNSPSC 51422333

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