Advanced Search



DL-α-Difluoromethylornithine hydrochloride hydrate

SIGMA/D193 - solid, ≥97% (NMR)

Synonym: 2-(Difluoromethyl)ornithine hydrochloride hydrate; DFMO hydrochloride hydrate; Eflornithine hydrochloride hydrate

CAS Number: 70052-12-9 (free base)
Empirical Formula (Hill Notation): C6H12F2N2O2 · xHCl · yH2O
Molecular Weight: 182.17 (anhydrous free base basis)
MDL Number: MFCD00242734
Linear Formula: C6H12F2N2O2 · xHCl · yH2O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-D193-25MG 25 mg
 $266.00
1/EA		 Add To Favorites
45-D193-100MG 100 mg
 $798.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D193-100MG

 

assay ≥97% (NMR)
color white
form solid
InChI 1S/C6H12F2N2O2.ClH.H2O/c7-4(8)6(10,5(11)12)2-1-3-9;;/h4H,1-3,9-10H2,(H,11,12);1H;1H2
InChI key FJPAMFNRCFEGSD-UHFFFAOYSA-N
Quality Level 100 
SMILES string O.Cl.NCCCC(N)(C(F)F)C(O)=O
solubility DMSO: >10 mg/mL
  H2O: >10 mg/mL
Application: DL-α-Difluoromethylornithine hydrochloride hydrate has been used to reduce the effects of arginine on cell proliferation. It has also been used to investigate the effect of bisphenol A (BPA) on the migration of an established ovine trophectoderm (oTr1) cell line.
Biochem/physiol Actions: Difluoromethylornithine (Eflornithine) inhibits polyamine biosynthesis by the selective, irreversible inhibition of ornithine decarboxylase (ODC). A chemoprotective agent that blocks angiogenesis.
Biochem/physiol Actions: Inhibits polyamine biosynthesis by selective, irreversible inhibition of ornithine decarboxylase. Chemoprotective agent that blocks angiogenesis.
General description: Difluoromethylornithine is a fluorinated ornithine analog, which acts as a rate-limiting enzyme of polyamine biosynthesis. It is used to treat female facial hirsutism and human African trypanosomiasis. Difluoromethylornithine functions as a chemopreventive and chemotherapeutic agent against neuroblastoma and colorectal cancer. It exhibits cytostatic effects on mammalian cells and tissues.
Packaging: 25, 100 mg in poly bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥97% (NMR)
UNSPSC 12352200

The following items have been added to your cart:

Choose a favorite list for this item:
Catalog Number Description Price
$

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.


Quick Order

* Required


New Year Price Updates

We are currently working diligently to update our website pricing information for the New Year. If you place an order, you will be acknowledged with any corrected pricing. If you'd like the most current information sooner, please don't hesitate to drop us an email or give us a call and we'd be happy to assist. Thank you for your patience while we are updating.

800-334-7725
office@krackeler.com


Play Video

To Request a Quote

  1. Search or Browse for items and add to them to your Shopping Cart.
  2. Click the "Request Quote" button at the bottom of the Shopping Cart page.
  3. Fill out required fields.
  4. Optionally you can convert to standard checkout mode by choosing a payment type.
  5. Click "Request Quote" at the bottom of the page.

You will be contacted with a quote.

To Order From a Quote

  1. Register and login to the website.
  2. Receive a quote from your sales representative or customer service.
  3. Have your copy of the quote in hand.
  4. Visit our quote module to search for your quote.
Back to Top