6-(Dimethylamino)purine
SIGMA/D2629 - ≥98%
Synonym: 6-DMAP; N6,N6-Dimethyladenine
CAS Number: 938-55-6
Empirical Formula (Hill Notation): C7H9N5
Molecular Weight: 163.18
EC Number: 213-344-3
MDL Number: MFCD00005573
Linear Formula: C7H9N5
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D2629-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D2629-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D2629-250MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D2629-500MG
| assay | ≥98% |
| biological source | synthetic (organic) |
| form | powder |
| InChI | 1S/C7H9N5/c1-12(2)7-5-6(9 |
| InChI key | BVIAOQMSVZHOJM-UHFFFAOYSA |
| mp | 259-262 °C (lit.) |
| Quality Level | 100  |
| SMILES string | CN(C)c1ncnc2[nH]cnc12 |
| solubility | water: 50 mg/mL, clear to hazy, colorless to light yellow |
| storage temp. | −20°C |
| Application: | 6-(Dimethylamino)purine has been used: • as a supplement in GR-1 aa medium (bovine medium) for parthenogenetic activation of bovine oocytes to study its potential for embryo development • in the activation step during the production of nuclear transfer embryos • as a supplement in HCR2aa medium to activate interspecies embryos derived from interspecies somatic cell nuclear transfer (iSCNT) technique |
| Biochem/physiol Actions: | 6-(Dimethylamino)purine (6-DMAP) is a protein kinase and cyclin-dependent kinase inhibitor. It acts as a secondary metabolite and mediates RNA modification. 6-DMAP is a potent cytokinetic inhibitor and is used in parthenogenesis and meiosis studies. It is also used to promote pronuclei formation in mammalian oocytes. 6-DMAP is a dual fluorescence molecule according to femtosecond fluorescence up-conversion spectroscopy studies. |
| General description: | 6-(Dimethylamino)purine (6-DMAP) is a purine-based metabolite with two condensed heterocyclic rings and two methyl groups linked to the amino group of the purine unit of adenine. |
| Packaging: | 1 g in poly bottle |
| Packaging: | 100, 250, 500 mg in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% |
| mp | 259-262 °C (lit.) |
| Storage Temp. | −20°C |
| UNSPSC | 41106305 |