Diphenhydramine hydrochloride
SIGMA/D3630 - ≥98% (HPLC)
Synonym: 2-Diphenylmethoxy-N,N-dimethylethylamine hydrochloride; N-
CAS Number: 147-24-0
Empirical Formula (Hill Notation): C17H21NO · HCl
Molecular Weight: 291.82
EC Number: 205-687-2
MDL Number: MFCD00012479
Linear Formula: C17H21NO · HCl
Product Type: Chemical
FT-IR Spectra for 2-Diphenylmethoxy-N,N-dimethylethylamine hydrochloride.
FT-NMR Spectra for 2-Diphenylmethoxy-N,N-dimethylethylamine hydrochloride.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D3630-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D3630-50G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D3630-5G
| assay | ≥98% (HPLC) |
| form | powder |
| InChI | 1S/C17H21NO.ClH/c1-18(2)1 |
| InChI key | PCHPORCSPXIHLZ-UHFFFAOYSA |
| originator | Johnson & Johnson |
| Quality Level | 200  |
| SMILES string | Cl[H].CN(C)CCOC(c1ccccc1) |
| Application: | Diphenhydramine hydrochloride has been used: as a reference compound to study the long duration of action of antihistamine bilastine in vivo to detect its embryotoxicity by embryonic stem cell test (EST) using cardiomyocyte differentiation and osteoblasts differentiation as an antihistamine in experimental studies |
| Biochem/physiol Actions: | H1 histamine receptor antagonist Diphenhydramine hydrochloride (DPH) is an antihistaminic agent that relieves symptoms of hypersensitive reactions. It exhibits antimuscarinic and marked sedative effects. DPH is also used to prevent nausea, vomiting and vertigo of various causes. In addition, it acts as a potential therapeutic for insomnia. |
| Features and Benefits: | This compound was developed by Johnson & Johnson . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| Packaging: | 5, 50, 100 g in glass bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| Safety Statements | 36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| UNSPSC | 12352116 |