Diamide
SIGMA/D3648
Synonym: 1,1′-Azobis(N,N-dimethylformamide); N,N,N′,N′-Tetramethylazodicarboxamide; Azodicarboxylic acid bis(dimethylamide); Diazenedicarboxylic acid bis(N,N-dimethylamide); TMAD
CAS Number: 10465-78-8
Empirical Formula (Hill Notation): C6H12N4O2
Molecular Weight: 172.19
EC Number: 233-951-7
MDL Number: MFCD00008318
Linear Formula: (CH3)2NCON=NCON(CH3)2
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D3648-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D3648-5G
| assay | ≥98% (TLC) |
| form | powder |
| InChI | 1S/C6H12N4O2/c1-9(2)5(11) |
| InChI key | VLSDXINSOMDCBK-BQYQJAHWSA |
| mp | 113-115 °C |
| Quality Level | 200  |
| SMILES string | CN(C)C(=O)N=NC(=O)N(C)C |
| solubility | water: 19.60-21.00 mg/mL, clear to slightly hazy, orange |
| storage temp. | −20°C |
| Application: | Reported to be of use as a thiol oxidizing agent. Diamide has been used to titrate protein glutathiolation to discriminate from other oxidative protein modifications. Treatment increased protein glutathiolation in a concentration-dependent manner and had comparably little effect on protein-protein disulfide formation. |
| Packaging: | 5 g in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (TLC) |
| mp | 113-115 °C |
| Storage Temp. | −20°C |
| UNSPSC | 12352102 |