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3,3′-Dithiodipropionic acid di(N-hydroxysuccinimide ester)

SIGMA/D3669 - powder

Synonym: DTSP; Di(N-succinimidyl) 3,3′-dithiodipropionate; Dithiobis(succinimidyl propionate); Lomant’s reagent

CAS Number: 57757-57-0
Empirical Formula (Hill Notation): C14H16N2O8S2
Molecular Weight: 404.42
EC Number: 260-931-5
MDL Number: MFCD00042045
Linear Formula: C14H16N2O8S2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-D3669-500MG 500 mg
 $235.00
1/EA		 Add To Favorites
45-D3669-1G 1 g
 $429.00
1/EA		 Add To Favorites

 

form powder
InChI 1S/C14H16N2O8S2/c17-9-1-2-10(18)15(9)23-13(21)5-7-25-26-8-6-14(22)24-16-11(19)3-4-12(16)20/h1-8H2
InChI key FXYPGCIGRDZWNR-UHFFFAOYSA-N
Quality Level 200 
reaction suitability reagent type: cross-linking reagent
SMILES string O=C(CCSSCCC(=O)ON1C(=O)CCC1=O)ON2C(=O)CCC2=O
solubility acetone: soluble
  chloroform: 50 mg/mL
  DMF: soluble
storage temp. −20°C
Application: 3,3′-Dithiodipropionic acid di(N-hydroxysuccinimide ester) (DSP) has been used as a protein cross-linker.
Disclaimer: Avoid use of reducing agents during coupling reactions.
Features and Benefits: The disulfide linkage is cleavable by mild reduction.
General description: 3,3′-Dithiodipropionic acid di(N-hydroxysuccinimide ester) (DSP) is a homobifunctional cross-linking reagent containing a cleavable disulfide linkage. It is typically coupled to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5).
Storage Temp. −20°C
UNSPSC 12352106

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