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Dipeptidyl Peptidase IV Inhibitor I

SIGMA/D3822

Synonym: Diprotin A

Empirical Formula (Hill Notation): C17H31N3O4
Molecular Weight: 341.45
Linear Formula: C17H31N3O4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-D3822-5MG 5 mg
 $265.00
1/EA		 Add To Favorites
This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.

 

assay ≥95% (HPLC)
color white
form solid
Quality Level 200 
storage temp. 2-8°C
Application: Dipeptidyl peptidase IV inhibitor I has been used in acute in vivo studies to assess rapid plasma glucagon-like peptide (GLP-1) responses to specified secretory agents in mice.
Biochem/physiol Actions: Dipeptidyl peptidase IV (DPP IV) functions as a modulator of glucagon-like peptide (GLP-1), insulin-stimulating hormones, and glucose-dependent insulinotropic polypeptide (GIP). It is an essential therapeutic target for type 2 diabetes (T2DM). DPP-4 inhibitors are crucial for maintaining glucose homeostasis by prolonging the activity of GLP-1 and GIP. They also enhance glycemic control for a longer period when compared to early oral hypoglycemics. DPP-4 also acts as a binding protein and a ligand of extracellular factors.
General description: Dipeptidyl peptidase IV (DPP IV) is a member of the prolyl-specific proteases family. It is a dimeric type II integral membrane glycoprotein that is broadly expressed in the epithelial and nonepithelial tissues. It is majorly expressed in the kidney and the colon. 
Other Notes: Ile-Pro-Ile
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥95% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352202

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