2′-Deoxycytidine

SIGMA/D3897 - ≥99% (HPLC)

Synonym: Cytosine deoxyriboside

CAS Number: 951-77-9
Empirical Formula (Hill Notation): C₉H₁₃N₃O₄
Molecular Weight: 227.22
EC Number: 213-454-1
MDL Number: MFCD00006547
Linear Formula: C₉H₁₃N₃O₄
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-D3897-100MG	100 mg	$62.30 1/EA	Add To Favorites
45-D3897-250MG	250 mg	$66.30 1/EA	Add To Favorites
45-D3897-500MG	500 mg	$90.30 1/EA	Add To Favorites
45-D3897-1G	1 g	$151.00 1/EA	Add To Favorites
45-D3897-5G	5 g	$496.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D3897-100MG

Properties
Descriptions
Safety Info.
Basic Data

assay	≥99% (HPLC)
biological source	synthetic (organic)
form	powder
InChI	1S/C9H13N3O4/c10-7-1-2-12(9(15)11-7)8-3-5(14)6(4-13)16-8/h1-2,5-6,8,13-14H,3-4H2,(H2,10,11,15)/t5-,6+,8+/m0/s1
InChI key	CKTSBUTUHBMZGZ-SHYZEUOFSA-N
Quality Level	200
SMILES string	NC1=NC(=O)N(C=C1)[C@H]2C[C@H](O)[C@@H](CO)O2
solubility	water: 50 mg/mL, clear, colorless to very faintly yellow
storage temp.	−20°C

Application:	2′-Deoxycytidine has been used: • as a substrate for Trypanosoma brucei cytidine deaminase (TbCDA) to measure its activity • as a standard in the isolation and quantification of metabolite levels in murine tumor interstitial fluid by liquid chromatography-mass spectrometry (LC–MS) • to study the role of autophagy in response to oncogenes and DNA replication stress
Biochem/physiol Actions:	2′-Deoxycytidine (deoxyC) forms dCTP upon phosphorylation which is used to synthesis DNA via various DNA polymerases or reverse transcriptases. DeoxyC is the substrate for deoxycytidine deaminase (EC 3.5.4.14) which converts it into 2′-deoxyuridine. DeoxyC is phosphorylated to the nucleotide dCMP by the enzyme deoxycytidine kinase (DCK). DeoxyC serves as a potential head and neck cancer marker.
General description:	2′-Deoxycytidine (deoxyC) is one of the deoxynucleosides containing cytosine as the nucleobase. It is found in the blood, feces, and urine.
Packaging:	1, 5 g in poly bottle
Packaging:	100, 250, 500 mg in poly bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥99% (HPLC)
Storage Temp.	−20°C
UNSPSC	41106305

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