Desipramine hydrochloride
SIGMA/D3900 - ≥98% (TLC), powder
CAS Number: 58-28-6
Empirical Formula (Hill Notation): C18H22N2 · HCl
Molecular Weight: 302.84
EC Number: 200-373-1
MDL Number: MFCD00058108
Linear Formula: C18H22N2 · HCl
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D3900-25G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D3900-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D3900-5G
| assay | ≥98% (TLC) |
| color | white to off-white |
| form | powder |
| InChI | 1S/C18H22N2.ClH/c1-19-13- |
| InChI key | XAEWZDYWZHIUCT-UHFFFAOYSA |
| originator | Sanofi Aventis |
| Quality Level | 100  |
| SMILES string | Cl[H].CNCCCN1c2ccccc2CCc3 |
| solubility | H2O: 50 mg/mL |
| storage temp. | 2-8°C |
| Application: | Desipramine hydrochloride has been used: • to prevent norepinephrine neuron degeneration and to maximize uptake into DA neurons • to protect unselective damage to the noradrenergic system • as a norepinephrine re-uptake inhibitor to treat rats for lesioning |
| Biochem/physiol Actions: | Desipramine is used to treat depression. It is also used to manage enuresis in children. Desipramine helps to eliminate the pain triggered by diabetic neuropathy. |
| Biochem/physiol Actions: | Tricyclic antidepressant that is a more potent inhibitor of the norepinephrine transporter (Ki = 4 nM) than the serotonin transporter (Ki = 61 nM). |
| Disclaimer: | Hygroscopic |
| Features and Benefits: | This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Features and Benefits: | This compound was developed by Sanofi Aventis . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| General description: | Desipramine, a metabolite of imipramine and iofepramine is an active tricyclic antidepressant. |
| Packaging: | 1, 5, 25 g in glass bottle |
| Symbol |   GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H302 - H315 - H317 - H319 - H334 - H335 |
| Precautionary statements | P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38-42/43 |
| Safety Statements | 22-24-26-36/37 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (TLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352116 |