trans-Dehydroandrosterone
SIGMA/D4000 - ≥99%
Synonym: 3β-Hydroxy-5-androsten-17-one; 5-Androsten-3β-ol-17-one; DHEA; Dehydroepiandrosterone; Dehydroisoandrosterone; Prasterone
CAS Number: 53-43-0
Empirical Formula (Hill Notation): C19H28O2
Molecular Weight: 288.42
EC Number: 200-175-5
MDL Number: MFCD00003613
Linear Formula: C19H28O2
Product Type: Chemical
| assay | ≥99% |
| biological source | synthetic (organic) |
| drug control | Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada |
| form | crystalline powder |
| InChI | 1S/C19H28O2/c1-18-9-7-13( |
| InChI key | FMGSKLZLMKYGDP-USOAJAOKSA |
| mp | 149-151 °C (lit.) |
| Quality Level | 200 ![]() |
| shipped in | ambient |
| SMILES string | C[C@]12CC[C@H]3[C@@H](CC= |
| solubility | chloroform: 50 mg/mL, clear, colorless |
| storage temp. | room temp |
| Biochem/physiol Actions: | Dehydroandrosterone (DHEA) is a negative modulator of GABAA receptors. It is a steroid secreted by the adrenal gland with both estrogenic and androgenic properties. DHEAs conversion to 5-androstenediol, a potent estrogen, enhances the growth and survival of estrogen-sensitive breast tumors. |
| Biochem/physiol Actions: | Negative modulator of GABAA receptors. Steroid secreted by the adrenal gland with both estrogenic and androgenic properties. Its conversion to 5-androstenediol, a potent estrogen, enhances the growth and survival of estrogen-sensitive breast tumors. |
| Biochem/physiol Actions: | Negative modulator of GABAA receptors. Steroid secreted by the adrenal gland with both estrogenic and androgenic properties. Its conversion to 5-androstenediol, a potent estrogen, enhances the growth and survival of estrogen-sensitive breast tumors. At high but physiologically valid concentrations, DHEA inhibits proliferation of chromaffin progenitor cells and induces dopaminergic differentiation. |
| Packaging: | 10, 25, 100, 250 g in poly bottle |
| Symbol | ![]() GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H351 - H360F - H362 - H410 |
| Precautionary statements | P201 - P202 - P260 - P263 - P273 - P308 + P313 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | UN 3077 9 / PGIII |
| WGK Germany | WGK 2 |
| Purity | ≥99% |
| mp | 149-151 °C (lit.) |
| Storage Temp. | room temp |
| UNSPSC | 51111800 |



