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5, 15-DPP

SIGMA/D4071

Synonym: 5,15-Diphenyl-21H,23H-porphine; 5,15-Diphenylporphyrin; 5,15-diphenyl-Porphine

CAS Number: 22112-89-6
Empirical Formula (Hill Notation): C32H22N4
Molecular Weight: 462.54
MDL Number: MFCD08276335
Linear Formula: C32H22N4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-D4071-10MG 10 mg
 $96.50
1/EA		 Add To Favorites
45-D4071-50MG 50 mg
 $290.00
1/EA		 Add To Favorites

 

form powder
InChI 1S/C32H22N4/c1-3-7-21(8-4-1)31-27-15-11-23(33-27)19-25-13-17-29(35-25)32(22-9-5-2-6-10-22)30-18-14-26(36-30)20-24-12-16-28(31)34-24/h1-20,33,36H/b23-19-,24-20-,25-19-,26-20-,31-27-,31-28-,32-29-,32-30-
InChI key FNNOEKVUXXVPAI-DUVOQLPESA-N
Quality Level 100 
SMILES string c1ccc(cc1)-c2c3ccc(cc4ccc([nH]4)c(-c5ccccc5)c6ccc(cc7ccc2[nH]7)n6)n3
Application: 5, 15-DPP has been used as a signal transducer and activator of transcription 3 (STAT3) inhibitor:
• to analyze its effects on malignant peripheral nerve sheath tumor (MPNST) survival and proliferation
• to study its effects on the thymic stromal lymphopoietin (TSLP) modulation of nometastatic gene 23-H1 (NME1 or nm23-H1) expression in human trophoblasts
• to study its effects on 17β-estradiol and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced M2 polarization in human macrophages and endometrial stromal cells
Biochem/physiol Actions: 5, 15-DPP is a selective STAT3 inhibitor and a selective STAT3-SH2 antagonist
Packaging: 10, 50 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
UNSPSC 12352200

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