N^G,N^G-Dimethylarginine dihydrochloride

SIGMA/D4268

Synonym: asym-Dimethylarginine; ADMA

CAS Number: 220805-22-1
Empirical Formula (Hill Notation): C₈H₁₈N₄O₂ · 2HCl
Molecular Weight: 275.18
MDL Number: MFCD00270857
Linear Formula: C₈H₁₈N₄O₂ · 2HCl
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-D4268-10MG	10 mg	$89.00 1/EA		Add To Favorites
45-D4268-50MG	50 mg	$310.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (TLC)
form	powder
InChI	1S/C8H18N4O2.2ClH/c1-12(2)8(10)11-5-3-4-6(9)7(13)14;;/h6H,3-5,9H2,1-2H3,(H2,10,11)(H,13,14);2*1H/t6-;;/m0../s1
InChI key	SYLNVYJOPZWPJI-ILKKLZGPSA-N
Quality Level	200
SMILES string	Cl[H].Cl[H].CN(C)C(=N)NCCC[C@H](N)C(O)=O
solubility	water: 50 mg/mL, clear, colorless
storage temp.	room temp

Application:	N^G,N^G- Dimethylarginine dihydrochloride has been used: • to study its effects on cardiovascular activities in rostral ventrolateral medulla (RVLM) in rats • as a standard for measuring L-arginine and dimethylarginines • to study its effects on hepatic deterioration
Biochem/physiol Actions:	Reversible inhibitor of nitric oxide synthetase in vivo and in vitro.
General description:	N^G,N^G-Dimethylarginine dihydrochloride is a methylated arginine derivative, which is produced by the liver. It is linked to liver cirrhosis, alcoholic hepatitis and acute liver failure (ALF).
Packaging:	10, 50 mg in poly bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (TLC)
Storage Temp.	room temp
UNSPSC	12352209

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