Dihydroeponemycin

SIGMA/D4321 - ≥98% (HPLC)

CAS Number: 126463-64-7
Empirical Formula (Hill Notation): C₂₀H₃₆N₂O₆
Molecular Weight: 400.51
MDL Number: MFCD17215971
Linear Formula: C₂₀H₃₆N₂O₆
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-D4321-5MG	5 mg	$1210.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	off-white to light tan
form	powder
InChI	1S/C20H36N2O6/c1-13(2)7-5-6-8-17(25)21-16(10-23)19(27)22-15(9-14(3)4)18(26)20(11-24)12-28-20/h13-16,23-24H,5-12H2,1-4H3,(H,21,25)(H,22,27)/t15-,16-,20+/m0/s1
InChI key	IUDBVFIQSSOIDB-TWOQFEAHSA-N
optical activity	[α]/D ±35.7°
Quality Level	100
SMILES string	CC(C)CCCCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(CO)CO1
solubility	DMSO: ≥1 mg/mL
storage temp.	2-8°C

Biochem/physiol Actions:	Dihydroeponemycin is an active derivative of eponemycin an antitumor antibiotic isolated from Streptomyces hygroscopicus. Dihydroeponemycin labels the catalytic threonine residues of the immunoproteasome subunits LMP2 and LMP7 and the constitutive proteasome subunit X, while epoxomicin covalently modifies the N-terminal catalytic threonine residues of the constitutive proteasome (X and Z) and immunoproteasome (LMP7 and MECL1) subunits.
Biochem/physiol Actions:	Dihydroeponemycin is an active derivative of eponemycin an antitumor antibiotic isolated from Streptomyces hygroscopicus.
Packaging:	1, 5 mg in glass bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H302
Hazard Codes	Xn
Risk Statements	22
RIDADR	NONH for all modes of transport
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352202

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