Doxepin hydrochloride
SIGMA/D4526 - ~85% E-isomer basis, ≥98% (GC), 15% Z-isomer basis, powder
Synonym: 11-
CAS Number: 1229-29-4
Empirical Formula (Hill Notation): C19H21NO · HCl
Molecular Weight: 315.84
EC Number: 214-966-8
MDL Number: MFCD00079135
Linear Formula: C19H21NO · HCl
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D4526-1G
| assay | ≥98% (GC) |
| color | white to off-white |
| composition | E-isomer, ~85% |
| Z-isomer, 15% | |
| form | powder |
| InChI | 1S/C19H21NO.ClH/c1-20(2)1 |
| InChI key | MHNSPTUQQIYJOT-SJDTYFKWSA |
| originator | Boehringer Ingelheim |
| Quality Level | 200  |
| SMILES string | Cl[H].CN(C)CCC=C1/c2cccc |
| solubility | 1 M HCl: 50 mg/mL |
| H2O: soluble |
| Biochem/physiol Actions: | Tricyclic antidepressant that is a more potent inhibitor of norepinephrine uptake than of serotonin uptake; antagonist at H1 histamine, muscarinic cholinergic, and α-adrenoreceptors. |
| Features and Benefits: | This compound was developed by Boehringer Ingelheim . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| General description: | Doxepin is used to treat chronic idiopathic urticaria, chronic pain and anxiety. Doxepin exhibits antiserotonergic properties. |
| Other Notes: | Mixture of cis- and trans-isomers |
| Packaging: | 1, 5 g in glass bottle |
| Symbol |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P301 + P310 |
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 36/37/39-45 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (GC) |
| UNSPSC | 12352200 |