Diethylstilbestrol
SIGMA/D4628 - ≥99% (HPLC)
Synonym: (E)
CAS Number: 56-53-1
Empirical Formula (Hill Notation): C18H20O2
Molecular Weight: 268.35
EC Number: 200-278-5
MDL Number: MFCD00002373
Linear Formula: C18H20O2
Product Type: Chemical
| assay | ≥99% (HPLC) |
| form | powder |
| InChI | 1S/C18H20O2/c1-3-17(13-5- |
| InChI key | RGLYKWWBQGJZGM-ISLYRVAYSA |
| Quality Level | 200  |
| SMILES string | CCC(c1ccc(O)cc1)=C(CC)c |
| Application: | Diethylstilbestrol has been used: • to evaluate the estrogenic activity of diethylstilbestrol by quantitating the expression levels of endogenous estrogen-regulated marker genes • to evaluate the estrogenic, androgenic and toxicity responses in bioluminescent yeast bioreporter assay (BLYES) • to detect its effect on the proliferation and tyrosinase activity of melanocytes |
| Biochem/physiol Actions: | Diethylstilbestrol is a synthetic estrogen with carcinogenic properties. Causes renal clear-cell carcinoma in Syrian hamster. In humans it causes increased risk of breast cancer, clear cell adenocarcinoma (CCA) of the vagina and cervix, and reproductive anomalies. Used in the treatment of prostate cancer to block the production of testosterone. |
| Symbol |    GHS07,GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H315 - H319 - H335 - H350 - H360 - H410 |
| Precautionary statements | P201 - P273 - P302 + P352 - P305 + P351 + P338 - P308 + P313 |
| Hazard Codes | T,N |
| Risk Statements | 45-61-36/37/38-51/53 |
| Safety Statements | 53-36/37/39-45-60-61 |
| RIDADR | UN 3077 9 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99% (HPLC) |
| UNSPSC | 51111800 |