n-Dodecyl β-D-maltoside
SIGMA/D4641 - ≥98% (GC)
Synonym: DDM; Lauryl-β-D-maltoside
CAS Number: 69227-93-6
Empirical Formula (Hill Notation): C24H46O11
Molecular Weight: 510.62
MDL Number: MFCD00043012
Linear Formula: C24H46O11
Product Type: Chemical
| aggregation number | 98 |
| assay | ≥98% (GC) |
| biological source | corn |
| CMC | 0.15 mM (20-25°C) |
| description | non-ionic |
| form | powder |
| impurities | <1.5% water (Karl Fischer) |
| InChI | 1S/C24H46O11/c1-2-3-4-5-6 |
| InChI key | NLEBIOOXCVAHBD-QKMCSOCLSA |
| mol wt | micellar avg mol wt 50,000 |
| mp | 224-226 °C (lit.) |
| Quality Level | 200 ![]() |
| SMILES string | CCCCCCCCCCCCO[C@@H]1O[C@H |
| solubility | water: 50 mg/mL, clear to very slightly hazy, colorless |
| storage temp. | −20°C |
| technique(s) | protein quantification: suitable |
| Application: | n-Dodecyl β-D-maltoside has been used in a study to assess the mapping of unfolding states of integral helical membrane proteins by GPS-NMR and scattering techniques. |
| Application: | Non-ionic detergent for the stabilization and activation of enzymes and for membrane research. |
| Application: | Non-ionic detergent used to extract and solubilize proteins. |
| Features and Benefits: | • Highly versatile surfactant for your cell biology and biochemical research • Suitable for protein quantification |
| General description: | N-dodecyl-β-D-maltoside, also known as Lauryl Maltoside, stands as a non-ionic surfactant and derivative of pyrene (Py). Functioning as an alkyl maltopyranoside detergent, it excels particularly in the solubilization and crystallization of membrane proteins, making it a crucial tool in cell biology and biochemical research. Its unique capability arises from its adeptness at forming micelles that mimic the membrane environment, thereby preserving the α-helical structures and native conformations of membrane-associated proteins. In addition to its primary function, N-dodecyl-β-D-maltoside has diverse applications, including the purification and stabilization of RNA polymerase, the detection of protein-lipid interactions, and serving as a substrate for glucosyl and xylosyl transfer by glycogenin. Its mild and non-denaturing properties have further led to its utilization in protein-anesthetic studies. Overall, N-dodecyl-β-D-maltoside emerges as a versatile detergent with a broad range of applications in membrane protein research and beyond. Its pivotal role in preserving protein structure and function establishes it as an indispensable tool for exploring the intricacies of membrane biology. |
| Other Notes: | For additional information on our range of Biochemicals , please complete this form . |
| Packaging: | 1, 5, 25 g in poly bottle |
| Packaging: | 500 mg in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (GC) |
| mp | 224-226 °C (lit.) |
| Storage Temp. | −20°C |
| UNSPSC | 12161900 |

