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n-Dodecyl β-D-maltoside

SIGMA/D4641 - ≥98% (GC)

Synonym: DDM; Lauryl-β-D-maltoside

CAS Number: 69227-93-6
Empirical Formula (Hill Notation): C24H46O11
Molecular Weight: 510.62
MDL Number: MFCD00043012
Linear Formula: C24H46O11
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-D4641-500MG 500 mg
$179.00
1/EA
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45-D4641-1G 1 g
$258.00
1/EA
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45-D4641-5G 5 g
$869.00
1/EA
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45-D4641-25G 25 g
$3240.00
1/EA
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FT-NMR Spectra for DDM.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: D4641-25G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: D4641-5G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: D4641-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: D4641-500MG

 

aggregation number 98
assay ≥98% (GC)
biological source corn
CMC 0.15 mM (20-25°C)
description non-ionic
form powder
impurities <1.5% water (Karl Fischer)
InChI 1S/C24H46O11/c1-2-3-4-5-6-7-8-9-10-11-12-32-23-21(31)19(29)22(16(14-26)34-23)35-24-20(30)18(28)17(27)15(13-25)33-24/h15-31H,2-14H2,1H3/t15-,16-,17-,18+,19-,20-,21-,22-,23-,24-/m1/s1
InChI key NLEBIOOXCVAHBD-QKMCSOCLSA-N
mol wt micellar avg mol wt 50,000
mp 224-226 °C (lit.)
Quality Level 200 
SMILES string CCCCCCCCCCCCO[C@@H]1O[C@H](CO)[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O
solubility water: 50 mg/mL, clear to very slightly hazy, colorless
storage temp. −20°C
technique(s) protein quantification: suitable
Application: n-Dodecyl β-D-maltoside has been used in a study to assess the mapping of unfolding states of integral helical membrane proteins by GPS-NMR and scattering techniques.
Application: Non-ionic detergent for the stabilization and activation of enzymes and for membrane research.
Application: Non-ionic detergent used to extract and solubilize proteins.
Features and Benefits: • Highly versatile surfactant for your cell biology and biochemical research
• Suitable for protein quantification

General description: N-dodecyl-β-D-maltoside, also known as Lauryl Maltoside, stands as a non-ionic surfactant and derivative of pyrene (Py). Functioning as an alkyl maltopyranoside detergent, it excels particularly in the solubilization and crystallization of membrane proteins, making it a crucial tool in cell biology and biochemical research. Its unique capability arises from its adeptness at forming micelles that mimic the membrane environment, thereby preserving the α-helical structures and native conformations of membrane-associated proteins.

In addition to its primary function, N-dodecyl-β-D-maltoside has diverse applications, including the purification and stabilization of RNA polymerase, the detection of protein-lipid interactions, and serving as a substrate for glucosyl and xylosyl transfer by glycogenin. Its mild and non-denaturing properties have further led to its utilization in protein-anesthetic studies. Overall, N-dodecyl-β-D-maltoside emerges as a versatile detergent with a broad range of applications in membrane protein research and beyond. Its pivotal role in preserving protein structure and function establishes it as an indispensable tool for exploring the intricacies of membrane biology.
Other Notes: For additional information on our range of Biochemicals , please complete this form .
Packaging: 1, 5, 25 g in poly bottle
Packaging: 500 mg in poly bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (GC)
mp 224-226 °C (lit.)
Storage Temp. −20°C
UNSPSC 12161900

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